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1. (WO2006012586) MODULATION OF FIAF AND THE GASTROINTESTINAL MICROBIOTA
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/012586 International Application No.: PCT/US2005/026213
Publication Date: 02.02.2006 International Filing Date: 25.07.2005
IPC:
A61K 31/00 (2006.01) ,A61K 38/00 (2006.01) ,A61K 49/00 (2006.01) ,C12Q 1/00 (2006.01) ,C07K 14/00 (2006.01)
Applicants: BACKHED, Fredrik[SE/US]; US (UsOnly)
RAWLS, John[US/US]; US (UsOnly)
SONNENBURG, Justin[US/US]; US (UsOnly)
HOOPER, Lora, V.[US/US]; US (UsOnly)
GORDON, Jeffrey[US/US]; US (UsOnly)
WASHINGTON UNIVERSITY IN ST. LOUIS[US/US]; One Brookings Drive St. Louis, MO 63130, US (AllExceptUS)
Inventors: BACKHED, Fredrik; US
RAWLS, John; US
SONNENBURG, Justin; US
HOOPER, Lora, V.; US
GORDON, Jeffrey; US
Agent: DOTY, Kathryn, J.; Polsinelli Shalton Welte Suelthaus PC 100 S. Fourth Street, Suite 1100 St. Louis, MO 63102 , US
Priority Data:
11/080,75515.03.2005US
60/591,31327.07.2004US
Title (EN) MODULATION OF FIAF AND THE GASTROINTESTINAL MICROBIOTA
(FR) MODULATION DE FIAF ET DE MICROBIOTE GASTRO-INTESTINAL
Abstract: front page image
(EN) The invention provides compositions and methods to modulate fat storage and weight loss in a subject. In certain aspects of the invention, fat storage (adiposity) and weight loss is modulated by altering the subject's gastrointestinal microbiota population. In other aspects of the invention, fat storage and weight loss is modulated by altering the amount of or the activity of the protein, fasting-induced adipocyte factor, in the subject.
(FR) L'invention concerne des compositions et des méthodes permettant de moduler l'accumulation de graisse et la perte de poids d'un sujet. Dans certains aspects de cette invention, l'accumulation de graisse (adiposité) et la perte de poids sont modulées par modification de la population de microbiote gastro-intestinal d'un sujet. Dans d'autres aspects de ladite invention, l'accumulation de graisse et la perte de poids sont modulées par modification de la quantité ou de l'activité de la protéine, du facteur adipeux induisant le jeûne, chez le sujet.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)