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1. (WO2006012419) INHIBITION OF NF-KB
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/012419    International Application No.:    PCT/US2005/025884
Publication Date: 02.02.2006 International Filing Date: 20.07.2005
A01N 43/42 (2006.01), A61K 31/44 (2006.01)
Applicants: CLEVELAND CLINIC FOUNDATION [US/US]; 9500 Euclid Avenue, Cleveland, OH 44195 (US) (For All Designated States Except US).
GUDKOV, Andrei, V. [US/US]; (US) (For US Only).
GUROVA, Katerina, V. [RU/US]; (US) (For US Only)
Inventors: GUDKOV, Andrei, V.; (US).
GUROVA, Katerina, V.; (US)
Agent: SCOTT, Teddy, C., Jr.; IP Docketing, Polsinelli Shalton Welte Suelthaus PC, Plaza Steppes Bldg., 700W. 47th St., Ste. 1000, Kansas City, MO 64112 (US)
Priority Data:
60/589,637 20.07.2004 US
Abstract: front page image
(EN)Aminoacridines are inhibitors of NF-κB. Inhibiting NF-κB leads to reactivation of p53 in cancer cells with functionally blocked p53.
(FR)Les aminoacridines sont des inhibiteurs de NF-?B. L'inhibition de NF-?B entraîne la réactivation de p53 dans les cellules cancéreuses dans lesquelles p53 est fonctionnellement bloquée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)