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1. (WO2006010544) 1, 1A, 5, 5A-TETRAHYDRO-3-THIA-CYCLOPROPA’A! PENTALENES: TRICYCLIC THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/010544    International Application No.:    PCT/EP2005/007892
Publication Date: 02.02.2006 International Filing Date: 20.07.2005
IPC:
C07D 333/78 (2006.01), C07D 409/12 (2006.01), A61K 31/4436 (2006.01), A61P 37/06 (2006.01)
Applicants: ACTELION PHARMACEUTICALS LTD [CH/CH]; Gewerbestrasse 16, CH-4123 Allschwill (CH) (For All Designated States Except US).
BOLLI, Martin [CH/CH]; (CH) (For US Only).
BUR, Daniel [CH/CH]; (CH) (For US Only).
CLOZEL, Martine [FR/CH]; (CH) (For US Only).
FISCHLI, Walter [CH/CH]; (CH) (For US Only).
LEHMANN, David [CH/CH]; (CH) (For US Only).
MATHYS, Boris [CH/CH]; (CH) (For US Only).
MUELLER, Claus [DE/DE]; (DE) (For US Only).
NAYLER, Oliver [CH/CH]; (CH) (For US Only).
SCHERZ, Michael [US/CH]; (CH) (For US Only).
WELLER, Thomas [CH/CH]; (CH) (For US Only)
Inventors: BOLLI, Martin; (CH).
BUR, Daniel; (CH).
CLOZEL, Martine; (CH).
FISCHLI, Walter; (CH).
LEHMANN, David; (CH).
MATHYS, Boris; (CH).
MUELLER, Claus; (DE).
NAYLER, Oliver; (CH).
SCHERZ, Michael; (CH).
WELLER, Thomas; (CH)
Agent: GSCHWEND, Thomas; Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, CH-4123 Allschwil (CH)
Priority Data:
PCT/EP2004/008501 29.07.2004 EP
Title (EN) 1, 1A, 5, 5A-TETRAHYDRO-3-THIA-CYCLOPROPA’A! PENTALENES: TRICYCLIC THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS
(FR) NOUVEAUX DERIVES DU THIOPHENE
Abstract: front page image
(EN)The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
(FR)La présente invention se rapporte à de nouveaux dérivés du thiophène, à leur préparation et à leur utilisation en tant que composés pharmaceutiquement actifs. Lesdits composés sont particulièrement actifs en tant qu'agents immunosuppresseurs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)