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1. (WO2006002064) ANTIBODY INHIBITING STEM CELL FACTOR ACTIVITY AND USE FOR TREATMENT OF ASTHMA
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2006/002064 International Application No.: PCT/US2005/021043
Publication Date: 05.01.2006 International Filing Date: 14.06.2005
IPC:
A61K 39/395 (2006.01) ,C07K 16/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
Applicants:
AEROVANCE, INC. [US/US]; 2929 Seventh Street Berkeley, CA 94710, US (AllExceptUS)
NEBEN, Steven [US/US]; US (UsOnly)
TAKEUCHI, Toshihiko [US/US]; US (UsOnly)
TOMKINSON, Adrian [US/US]; US (UsOnly)
DELARIA, Kathy [US/US]; US (UsOnly)
YAN, Kelly [US/US]; US (UsOnly)
WONG, Teresa [US/US]; US (UsOnly)
LONGPHRE, Malinda [US/US]; US (UsOnly)
Inventors:
NEBEN, Steven; US
TAKEUCHI, Toshihiko; US
TOMKINSON, Adrian; US
DELARIA, Kathy; US
YAN, Kelly; US
WONG, Teresa; US
LONGPHRE, Malinda; US
Agent:
HAILE, Lisa, A.; DLA Piper Rudnick Gray Cary US LLP Suite 1100 4365 Executive Drive San Diego, CA 92121-2133, US
Priority Data:
10/867,50614.06.2004US
60/579,46214.06.2004US
Title (EN) ANTIBODY INHIBITING STEM CELL FACTOR ACTIVITY AND USE FOR TREATMENT OF ASTHMA
(FR) ANTICORPS INHIBANT L'ACTIVITE DU FACTEUR DES CELLULES SOUCHES ET UTILISATION DE CES DERNIERS DANS LE TRAITEMENT DE L'ASTHME
Abstract:
(EN) The present invention provides human antibodies specific for stem cells factor that contain at least one CDR derived from a combinatorial antibody library. The invention also provides pharmaceutical compositions comprising the antibodies and methods of treating asthma. The invention further provides methods of detecting stem cell factor using the antibodies.
(FR) La présente invention concerne des anticorps humains qui sont dirigés spécifiquement contre le facteur des cellules souches contenant au moins un CDR provenant d'une bibliothèque combinatoire d'anticorps. Cette invention se rapporte également à des compositions pharmaceutiques comprenant les anticorps et des méthodes de traitement de l'asthme, ainsi que des méthodes de détection du facteur des cellules souches au moyen des anticorps.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)