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Machine translation
1. (WO2005123675) INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/123675    International Application No.:    PCT/GB2005/002404
Publication Date: 29.12.2005 International Filing Date: 17.06.2005
IPC:
C07D 209/42 (2006.01), C07D 401/04 (2006.01), C07D 401/14 (2006.01), A61K 31/404 (2006.01), A61P 29/00 (2006.01)
Applicants: BIOLIPOX AB [SE/SE]; P.O. Box 6280, S-102 34 Stockholm (SE) (For All Designated States Except US).
OLOFSSON, Kristofer [SE/SE]; (SE) (For US Only).
SUNA, Edgars [LV/LV]; (LV) (For US Only).
PELCMAN, Benjamin [SE/SE]; (SE) (For US Only).
OZOLA, Vita [LV/LV]; (LV) (For US Only).
KATKEVICS, Martins [LV/LV]; (LV) (For US Only).
KALVINS, Ivars [LV/LV]; (LV) (For US Only).
SCHAAL, Wesley [US/SE]; (SE) (For US Only)
Inventors: OLOFSSON, Kristofer; (SE).
SUNA, Edgars; (LV).
PELCMAN, Benjamin; (SE).
OZOLA, Vita; (LV).
KATKEVICS, Martins; (LV).
KALVINS, Ivars; (LV).
SCHAAL, Wesley; (SE)
Agent: MCNEENEY, Stephen; Eric Potter Clarkson, Park View House, 58 The Ropewalk, Nottingham NG1 5DD (GB)
Priority Data:
60/580,403 18.06.2004 US
Title (EN) INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION
(FR) INDOLES UTILES DANS LE TRAITEMENT DE L'INFLAMMATION
Abstract: front page image
(EN)There is provided a compound of formula (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
(FR)L'invention concerne un composé de la formule (I) où X, R1, R2, R3, R4, R5 et R6 ont la signification donnée dans la description, et leurs sels pharmaceutiquement acceptables, ces composés étant utiles dans le traitement de maladies dans lesquelles l'inhibition de l'activité de la prostaglandine E synthase-1 microsomale est souhaitée et/ou exigée, et notamment dans le traitement de l'inflammation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)