WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005123659) METHOD OF SYNTHESISING (1S)-4,5-DIMETHOXY-1- (METHYLAMINOMETHYL)-BENZOCYCLOBUTANE AND THE ADDITION SALTS THEREOF, AND USE OF SAME FOR THE SYNTHESIS OF IVABRADINE AND THE PHARMACEUTICALLY-ACCEPTABLE ADDITION SALTS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/123659    International Application No.:    PCT/FR2005/000397
Publication Date: 29.12.2005 International Filing Date: 21.02.2005
IPC:
C07C 213/10 (2006.01), C07C 217/56 (2006.01), C07B 57/00 (2006.01)
Applicants: LES LABORATOIRES SERVIER [FR/FR]; 12, Place de la Défense, F-92415 Courbevoie Cédex (FR) (For All Designated States Except US).
LERESTIF, Jean-Michel [FR/FR]; (FR) (For US Only).
GONZALES BLANCO, Isaac [ES/ES]; (ES) (For US Only).
LECOUVE, Jean-Pierre [FR/FR]; (FR) (For US Only).
BRIGOT, Daniel [FR/FR]; (FR) (For US Only)
Inventors: LERESTIF, Jean-Michel; (FR).
GONZALES BLANCO, Isaac; (ES).
LECOUVE, Jean-Pierre; (FR).
BRIGOT, Daniel; (FR)
Agent: LES LABORATOIRES SERVIER; 12, place de la Défense, F-92415 Courbevoie Cedex (FR)
Priority Data:
0405453 19.05.2004 FR
Title (EN) METHOD OF SYNTHESISING (1S)-4,5-DIMETHOXY-1- (METHYLAMINOMETHYL)-BENZOCYCLOBUTANE AND THE ADDITION SALTS THEREOF, AND USE OF SAME FOR THE SYNTHESIS OF IVABRADINE AND THE PHARMACEUTICALLY-ACCEPTABLE ADDITION SALTS THEREOF
(FR) PROCEDE DE SYNTHESE DU (1S)-4,5-DIMETHOXY-1- (METHYLAMINOMETHYL)-BENZOCYCLOBUTANE ET DE SES SELS D'ADDITION, ET APPLICATION A LA SYNTHESE DE L'IVABRADINE ET DE SES SELS D'ADDITION A UN ACIDE PHARMACEUTIQUEMENT ACCEPTABLE
Abstract: front page image
(EN)The invention relates to a method of synthesising a compound having formula (I) and to the use thereof for the synthesis of ivabradine and the pharmaceutically-acceptable acid addition salts and hydrates of same.
(FR)Procédé de synthèse du composé de formule (I) Application à la synthèse de l'ivabradine, de ses sels d'addition à un acide pharmaceutiquement acceptable et de ses hydrates.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)