WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005121787) LAT1 TRANSPORTERS EXPRESSED IN CANCER CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/121787    International Application No.:    PCT/US2005/020078
Publication Date: 22.12.2005 International Filing Date: 06.06.2005
Chapter 2 Demand Filed:    29.12.2005    
IPC:
G01N 33/50 (2006.01), A61K 49/00 (2006.01)
Applicants: XENOPORT, INC. [US/US]; 3410 Central Expressway, Santa Clara, CA 95051 (US) (For All Designated States Except US).
ZERANGUE, Noa [US/US]; (US) (For US Only)
Inventors: ZERANGUE, Noa; (US)
Agent: SANDBAKEN, Mark, G.; Townsend and Townsend and Crew LLP, Two Embarcadero Center, 8th Floor, San Francisco, CA 94111-3834 (US)
Priority Data:
60/577,130 04.06.2004 US
Title (EN) LAT1 TRANSPORTERS EXPRESSED IN CANCER CELLS
(FR) TRANSPORTEURS LAT1 EXPRIMES DANS LES CELLULES CANCEREUSES
Abstract: front page image
(EN)LAT1 is consistently expressed at high levels in cancer cells. Disclosed herein are assays for determining whether a test material/molecule is a substrate for, and/or is transported by, the LAT1 transporter, and therefore a candidate substrate for transport into cancer cells. The assays are useful in screening for cytotoxic agents or imaging components used in the treatment or diagnosis of cancer.
(FR)L'invention concerne des transporteurs LAT1 exprimés régulièrement à des niveaux élevés dans les cellules cancéreuses. L'invention concerne également des essais biologiques permettant de déterminer si une matière/molécule d'essai est un substrat pour, et/ou est transportée par, le transporteur LAT1, et donc si elle est un substrat candidat pour le transport dans les cellules cancéreuses. Les essais biologiques sont utiles dans le criblage des agents cytotoxiques ou des composants d'imagerie utilisés dans le traitement ou le diagnostic du cancer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)