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Machine translation
1. (WO2005121327) BIOSYNTHETIC GENE CLUSTER FOR THE PRODUCTION OF A COMPLEX POLYKETIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/121327    International Application No.:    PCT/US2005/019473
Publication Date: 22.12.2005 International Filing Date: 03.06.2005
IPC:
C12N 15/52 (2006.01), C12P 19/62 (2006.01), C07D 498/18 (2006.01)
Applicants: WYETH [US/US]; Five Giralda Farms, Madison, NJ 07940 (US) (For All Designated States Except US).
HE, Min [CN/US]; (US) (For US Only).
HUCUL, John [US/US]; (US) (For US Only).
HALTLI, Bradley, Arnold [US/US]; (US) (For US Only).
WAGENAAR, Melissa, M. [US/US]; (US) (For US Only).
GRAZIANI, Edmund [CA/US]; (US) (For US Only).
SUMMERS, Mia [CA/US]; (US) (For US Only).
KULOWSKI, Kerry [US/US]; (US) (For US Only).
PONG, Kevin [US/US]; (US) (For US Only).
FENG, Xidong [CN/US]; (US) (For US Only)
Inventors: HE, Min; (US).
HUCUL, John; (US).
HALTLI, Bradley, Arnold; (US).
WAGENAAR, Melissa, M.; (US).
GRAZIANI, Edmund; (US).
SUMMERS, Mia; (US).
KULOWSKI, Kerry; (US).
PONG, Kevin; (US).
FENG, Xidong; (US)
Agent: KODROFF, Cathy, A.; Howson and Howson, 321 Norristown Road, Suite 200, Spring House Corporate Center, P.O. Box 457, Spring House, PA 19477 (US)
Priority Data:
60/576,895 03.06.2004 US
60/664,483 23.03.2005 US
Title (EN) BIOSYNTHETIC GENE CLUSTER FOR THE PRODUCTION OF A COMPLEX POLYKETIDE
(FR) GROUPE DE GENES BIOSYNTHETIQUES UTILISE DANS LA PRODUCTION D'UN POLYKETIDE COMPLEXE
Abstract: front page image
(EN)A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described. Also provided are novel Streptomyces species and methods of modified Streptomyces species. Further described are novel compounds, 36-ketomeridamycin, C9-deoxomeridamycin, and C9-deoxoprolylmeridamcyin and uses thereof.
(FR)L'invention concerne un complexe polykétide synthase composé d'une polykétide synthase à 15 modules totaux, d'une peptide synthase non ribosomique à un module et d'une cytochrome P450 hydroxylase. L'invention concerne également de nouvelles espèces Streptomyces, ainsi que des procédés permettant d'obtenir des Streptomyces modifiées. L'invention concerne encore de nouveaux composés, 36-cétoméridamycine, C9-désoxoméridamycine et C9-désoxoprolylméridamycine, ainsi que leurs utilisations.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)