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Machine translation
1. (WO2005121106) 4-PHENYL-PYRIMIDINE-2-CARBONITRILE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/121106    International Application No.:    PCT/EP2005/006266
Publication Date: 22.12.2005 International Filing Date: 09.06.2005
IPC:
C07D 239/28 (2006.01), A61K 31/505 (2006.01), A61P 19/10 (2006.01)
Applicants: N.V. ORGANON [NL/NL]; Kloosterstraat 6, NL-5349 AB Oss (NL) (For All Designated States Except US).
CAI, Jiaqiang [CN/GB]; (GB) (For US Only).
RANKOVIC, Zoran [YU/GB]; (GB) (For US Only).
MOIR, Jennifer, Helen [GB/GB]; (GB) (For US Only)
Inventors: CAI, Jiaqiang; (GB).
RANKOVIC, Zoran; (GB).
MOIR, Jennifer, Helen; (GB)
Priority Data:
04253491.7 11.06.2004 EP
04106949.3 23.12.2004 EP
Title (EN) 4-PHENYL-PYRIMIDINE-2-CARBONITRILE DERIVATIVES
(FR) DERIVES 4-PHENYLE-PYRIMIDINE-2-CARBONITRILE
Abstract: front page image
(EN)The invention relates to 4-phenyl-pyrimidine-2-carbonitrile derivatives having the general formula (I) or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives as well as to the use thereof in the preparation of a medicament suitable for the treatment of osteoporosis, atherosclerosis, inflammation and immune disorders, such as rheumatoid arthritis, and chronic pain, such as neuropathic pain.
(FR)L'invention concerne des dérivés de 4-phényle-pyrimidine-2-carbonitrile représentés par la formule générale (I) ou un sel de ceux-ci acceptables sur le plan pharmaceutique. L'invention concerne également des compositions pharmaceutiques contenant ces dérivés ainsi que l'utilisation de celles-ci dans la préparation d'un médicament destiné au traitement de l'ostéoporose, de l'athérosclérose, de troubles inflammatoires et immunitaires, tels que la polyarthrite rhumatoïde, et les douleurs chroniques telles que les douleurs neuropathiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)