WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005120561) VACCINE AGAINST INFECTION BY A YERSINIA SPECIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/120561    International Application No.:    PCT/GB2005/002335
Publication Date: 22.12.2005 International Filing Date: 13.06.2005
IPC:
A61K 39/02 (2006.01)
Applicants: THE SECRETARY OF STATE FOR DEFENCE [GB/GB]; DSTL, Porton Down, Salisbury, Wiltshire SP4 0JQ (GB) (For All Designated States Except US).
ROBINSON, Victoria, Louise [GB/GB]; (GB) (For US Only).
OYSTON, Petra, Claire, Farquhar [GB/GB]; (GB) (For US Only).
TITBALL, Richard, William [GB/GB]; (GB) (For US Only)
Inventors: ROBINSON, Victoria, Louise; (GB).
OYSTON, Petra, Claire, Farquhar; (GB).
TITBALL, Richard, William; (GB)
Agent: BECKHAM, Robert, William; D/IPR Formalities Section, Poplar 2, MOD Abbey Wood#2218, Bristol BS34 8JH (GB)
Priority Data:
0413154.6 12.06.2004 GB
Title (EN) VACCINE AGAINST INFECTION BY A YERSINIA SPECIES
(FR) VACCIN
Abstract: front page image
(EN)A recombinant microorganism which is a recombinant Yersinia species which has been mutated so that DNA adenine methylase activity is downregulated, for use as a prophylactic or therapeutic vaccine against infection by a Yersinia species. In particular, the microorganism is an isogenic mutant, in which the dam gene is at least partially replaced, with for example a selection marker. These can provide cross protection against a range of Yersinia species such as Y. pestis and Y. pseudotuberculosis.
(FR)La présente invention a trait à un micro-organisme recombinant qui est une espèce Yersinia recombinante qui a subi une mutation de sorte que l'activité adénine méthylase d'ADN a été soumise à une régulation négative, en vue de son utilisation sous forme de vaccin prophylactique ou thérapeutique contre une infection par une espèce Yersinia. En particulier, le micro-organisme est un mutant isogènique, dans lequel le gène dam est au moins en partie substitué, par exemple par un marqueur de sélection. Ceux-ci peuvent assurer une protection croisée contre une variété d'espèces Yersinia, telles que la peste à Yersinia et la pseudotuberculose à Yersinia.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)