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Machine translation
1. (WO2005120558) METHODS FOR MAKING COMPOSITIONS COMPRISING HEAT SHOCK PROTEINS OR ALPHA-2-MACROGLOBULIN FOR THE TREATMENT OF CANCER AND INFECTIOUS DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/120558    International Application No.:    PCT/US2005/018471
Publication Date: 22.12.2005 International Filing Date: 25.05.2005
IPC:
A61K 31/00 (2006.01), A61K 38/00 (2006.01), A01N 61/00 (2006.01), C07K 5/00 (2006.01), C07K 7/00 (2006.01), C07K 16/00 (2006.01), C07K 17/00 (2006.01)
Applicants: UNIVERSITY OF CONNECTICUT HEALTH CENTER [US/US]; 263 Farmington Avenue, Farmington, CT 06030 (US) (For All Designated States Except US).
SRIVASTAVA, Pramod, K. [IN/US]; (US) (For US Only)
Inventors: SRIVASTAVA, Pramod, K.; (US)
Agent: ANTLER, Adriane, M.; Jones Day, 222 East 41st Street, New York, NY 10017-6702 (US)
Priority Data:
60/574,510 25.05.2004 US
60/588,902 16.07.2004 US
Title (EN) METHODS FOR MAKING COMPOSITIONS COMPRISING HEAT SHOCK PROTEINS OR ALPHA-2-MACROGLOBULIN FOR THE TREATMENT OF CANCER AND INFECTIOUS DISEASE
(FR) PROCEDE POUR LA FABRICATION DE COMPOSITIONS COMPORTANT DES PROTEINES DE CHOC THERMIQUE OU DE L'ALPHA-2-MACROGLOBULINE POUR LE TRAITEMENT DU CANCER ET DE MALADIE INFECTIEUSE
Abstract: front page image
(EN)The present invention relates to methods for making complexes of HSP or alpha-2 macroglobulin and antigenic peptides, and uses of such complexes for the prevention and treatment of infectious diseases, cancers, and metabolic disorders. The methods of the invention comprises treating a purified target antigen preparation with a protease and/or a chemical to generate an antigenic set of peptides which is complexed to HSP or alpha-2 macroglobulin. Also encompassed in the invention are compositions comprising complexes of HSP or alpha-2 macroglobulin and antigenic peptides.
(FR)La présente invention a trait à des procédés pour la fabrication de complexes de HSP ou d'alpha-2 macroglobuline et de peptides antigéniques, et les utilisations de tels complexes pour la prévention et le traitement de maladies infectieuses, de cancers et de troubles métaboliques. Les procédés de l'invention comprennent le traitement d'une préparation purifiée d'antigènes cibles avec une protéase et/ou une substance chimique pour la génération d'un ensemble antigénique de peptides qui est complexé à la HSP ou l'alpha-2 macroglobuline. L'invention a également trait à des compositions comportant des complexes de HSP ou d'alpha-2 macroglobuline et de peptides antigéniques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)