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Machine translation
1. (WO2005120552) METHODS AND FORMULATIONS OF GnRH/LEUKOTOXIN CHIMERAS FOR TESTOSTERONE SUPPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/120552    International Application No.:    PCT/CA2005/000878
Publication Date: 22.12.2005 International Filing Date: 06.06.2005
IPC:
A61K 38/22 (2006.01), A61P 5/28 (2006.01), A61K 38/16 (2006.01), A61K 39/39 (2006.01), C07K 19/00 (2006.01), C07K 14/195 (2006.01), C07K 7/23 (2006.01), A61K 47/48 (2006.01), A61K 47/42 (2006.01)
Applicants: YM BIOSCIENCES INC. [CA/CA]; 5045 Orbitor Drive, Bldg. 11, Suite 400, Mississauga, Ontario L5H 1X8 (CA) (For All Designated States Except US).
STIERNHOLM, Niclas, B., J. [SE/CA]; (CA) (For US Only).
THOMPSON, Sean, E., L. [CA/CA]; (CA) (For US Only).
BINNIE, Craig [--/CA]; (CA) (For US Only).
KEANE, Paul, Michael [CA/CA]; (CA) (For US Only)
Inventors: STIERNHOLM, Niclas, B., J.; (CA).
THOMPSON, Sean, E., L.; (CA).
BINNIE, Craig; (CA).
KEANE, Paul, Michael; (CA)
Agent: ERRATT, Judy, A.; Gowling Lafleur Henderson LLP, 160 Elgin Street, suite 2600, Ottawa, Ontario K1P 1C3 (CA)
Priority Data:
2,467,769 11.06.2004 CA
60/579,354 14.06.2004 US
Title (EN) METHODS AND FORMULATIONS OF GnRH/LEUKOTOXIN CHIMERAS FOR TESTOSTERONE SUPPRESSION
(FR) PROCEDES ET FORMULATIONS DE CHIMERES DE GNRH/LEUCOTOXINE EN VUE DE LA SUPPRESSION DE TESTOSTERONE
Abstract: front page image
(EN)Compositions comprising immunogenic GnRH multimer/leukotoxin chimeras in combination with aluminum-based adjuvants and MontanideTm, are described. The compositions elicit anti-GnRH antibodies and are useful for suppressing testosterone levels, e.g., in males with prostate cancer.
(FR)Sont décrites des compositions comprenant des chimEres immunogEnes de multimEres de GnRH/leucotoxine combinEes avec des adjuvants A base d'aluminium et avec du MontanideTm. Ces compositions produisent des anticorps anti-GnRH et sont utiles pour la suppression de niveaux de testostErone, par exemple chez des individus mAles prEsentant un cancer de la prostate.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)