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Machine translation
1. (WO2005119525) 11&bgr;HSD1 CRYSTAL STRUCTURES FOR STRUCTURE BASED DRUG DESIGN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/119525    International Application No.:    PCT/IB2005/001463
Publication Date: 15.12.2005 International Filing Date: 23.05.2005
Chapter 2 Demand Filed:    11.07.2005    
IPC:
G06F 17/50 (2006.01), C12N 9/04 (2006.01)
Applicants: PFIZER PRODUCTS INC. [US/US]; Eastern Point Road, Groton, CT 06340 (US) (For All Designated States Except US).
CASTRO, Arturo, Antonio [US/US]; (US) (For US Only).
DING, Yuan-Hua [CN/US]; (US) (For US Only).
ERMOLIEFF, Jacques [FR/US]; (US) (For US Only).
HUGHES, Jason, Darryl [US/US]; (US) (For US Only).
JANOSKY, Christine, Loh [US/US]; (US) (For US Only).
KOHLS, Darcy, John, Reinard [CA/US]; (US) (For US Only).
LOW, Chee, Meng [MY/US]; (US) (For US Only).
MROCZKOWSKI, Barbara [US/US]; (US) (For US Only).
PAULY, Thomas, Adelbert [US/US]; (US) (For US Only).
REJTO, Paul, Abraham [US/US]; (US) (For US Only).
ZHANG, Yan [CA/US]; (US) (For US Only).
ZHU, Jeff, Xianchao [CN/US]; (US) (For US Only)
Inventors: CASTRO, Arturo, Antonio; (US).
DING, Yuan-Hua; (US).
ERMOLIEFF, Jacques; (US).
HUGHES, Jason, Darryl; (US).
JANOSKY, Christine, Loh; (US).
KOHLS, Darcy, John, Reinard; (US).
LOW, Chee, Meng; (US).
MROCZKOWSKI, Barbara; (US).
PAULY, Thomas, Adelbert; (US).
REJTO, Paul, Abraham; (US).
ZHANG, Yan; (US).
ZHU, Jeff, Xianchao; (US)
Agent: FULLER, Grover, F., Jr.; C/o LAWRENCE, Jackie, Pfizer Inc., MS8260-1615, Eastern Point Road, Groton, CT 06340 (US)
Priority Data:
60/576,955 04.06.2004 US
60/638,355 22.12.2004 US
Title (EN) 11&bgr;HSD1 CRYSTAL STRUCTURES FOR STRUCTURE BASED DRUG DESIGN
(FR) STRUCTURES CRISTALLINES DE 11?HSD1 UTILISEES POUR LA CONCEPTION DE MEDICAMENTS
Abstract: front page image
(EN)Crystalline compositions of 11 &bgr; Hydroxysteroid dehydrogenase (11&bgr;HSD1), and the nucleotide and amino acid sequences utilized to form such crystalline compositions. The crystalline compositions then used to screen 11&bgr;HSD1 ligands. The ligands are formulated into pharmaceutical compositions, and used for treatment of disease states or disorders mediated by 11&bgr;HSD1.
(FR)L'invention porte sur des compositions cristallines de 11 ? hydroxystéroïd déshydrogénase (11?HSD1), et sur les séquences de nucléotides et d'acides aminés utilisées pour former ces compositions, qu'on utilise pour le criblage de ligands du 11?HSD1. Lesdits ligands entrent dans la composition de préparations pharmaceutiques utilisées pour traiter les états morbides ou les troubles médiés par le 11?HSD1.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)