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1. (WO2005119267) ASSAY SYSTEM WITH IN SITU FORMATION OF DIAZO REAGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/119267    International Application No.:    PCT/US2005/018742
Publication Date: 15.12.2005 International Filing Date: 27.05.2005
IPC:
G01N 33/72 (2006.01)
Applicants: BECKMAN COULTER, INC. [US/US]; c/o D. David Hill, Esq., Counsel, Intellectual Property, 4300 North Harbor Boulevard, Fullerton, CA 92834-3100 (US) (For All Designated States Except US).
MU, Xihai [US/US]; (US) (For US Only).
CERNOSEK, Rose, Mary [US/US]; (US) (For US Only)
Inventors: MU, Xihai; (US).
CERNOSEK, Rose, Mary; (US)
Agent: FEDRICK, Michael, F.; Sheldon & Mak PC, 225 South Lake Avenue, 9th Floor, Pasadena, CA 91101 (US)
Priority Data:
10/858,673 01.06.2004 US
Title (EN) ASSAY SYSTEM WITH IN SITU FORMATION OF DIAZO REAGENT
(FR) SYSTEME DE DOSAGE AVEC FORMATION IN SITU DE REACTIF DIAZO
Abstract: front page image
(EN)A total bilirubin diazo assay is disclosed in which an acidic solution containing a primary aryl amine is combined directly with a nitrite-containing sample solution at approximately neutral pH, resulting in the in situ generation of a diazo compound in the sample solution. The diazo compound reacts with bilirubin in the sample solution to form a colored reaction product that can be measured.
(FR)L'invention concerne un dosage total de diazo-bilirubine : une solution acide contenant une aryle amine primaire est combinée directement avec une solution d'échantillon contenant nitrite à un pH approximativement neutre, ce qui permet de former in situ un composé diazo dans ladite solution. Le composé diazo réagit avec la bilirubine dans la solution pour former un produit de réaction coloré pouvant être mesuré.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)