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1. (WO2005118647) M13 VIRUS MAJOR COAT PROTEIN VARIANTS FOR C-TERMINAL AND BI-TERMINAL DISPLAY OF A HETEROLOGOUS PROTEIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118647    International Application No.:    PCT/US2005/017361
Publication Date: 15.12.2005 International Filing Date: 17.05.2005
IPC:
C07K 19/00 (2006.01), C12N 15/62 (2006.01)
Applicants: GENENTECH, INC. [US/US]; 1 DNA Way, South San Francisco, California 94080-4990 (US) (For All Designated States Except US).
HELD, Heike A. [DE/US]; (US) (For US Only).
SIDHU, Sachdev S. [CA/US]; (US) (For US Only)
Inventors: HELD, Heike A.; (US).
SIDHU, Sachdev S.; (US)
Agent: NAIK, Paul; Genentech, Inc., MS 49, 1 DNA Way, South San Francisco, CA 94080 (US)
Priority Data:
60/571,992 18.05.2004 US
Title (EN) M13 VIRUS MAJOR COAT PROTEIN VARIANTS FOR C-TERMINAL AND BI-TERMINAL DISPLAY OF A HETEROLOGOUS PROTEIN
(FR) PRINCIPAUX VARIANTS DE PROTEINES DE COQUE POUR AFFICHAGE C-TERMINAL ET BI-TERMINAL
Abstract: front page image
(EN)The invention provides compositions and methods for enhanced display of heterologous proteins on viral particles, using a fusion protein comprising a heterologous protein fused to a major coat protein of a virus, wherein the major coat protein is a variant of a wild type major coat protein of the virus and is capable of C-terminal display of the heterologous polypeptide.
(FR)L'invention concerne des compositions et des méthodes d'affichage amélioré de protéines hétérologues sur des particules virales.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)