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1. (WO2005118644) BINDING MOLECULES CAPABLE OF NEUTRALIZING RABIES VIRUS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118644    International Application No.:    PCT/EP2005/052410
Publication Date: 15.12.2005 International Filing Date: 26.05.2005
Chapter 2 Demand Filed:    06.04.2006    
IPC:
C07K 16/10 (2006.01), A61K 39/395 (2006.01), A61P 31/14 (2006.01), C12N 15/13 (2006.01), C12N 15/63 (2006.01), C12N 5/10 (2006.01)
Applicants: CRUCELL HOLLAND B.V. [NL/NL]; Archimedesweg 4, NL-2333 CN Leiden (NL) (For All Designated States Except US).
BAKKER, Alexander, Berthold, Hendrik [NL/NL]; (NL) (For US Only).
MARISSEN, Willem Egbert [NL/NL]; (NL) (For US Only).
KRAMER, Robert Arjen [NL/NL]; (NL) (For US Only).
DE KRUIF, Cornelis Adriaan [NL/NL]; (NL) (For US Only)
Inventors: BAKKER, Alexander, Berthold, Hendrik; (NL).
MARISSEN, Willem Egbert; (NL).
KRAMER, Robert Arjen; (NL).
DE KRUIF, Cornelis Adriaan; (NL)
Agent: KLEIN, Bart; Crucell Holland B.V., Archimedesweg 4, NL-2333 CN Leiden (NL)
Priority Data:
PCT/EP2004/050943 27.05.2004 EP
60/575,023 27.05.2004 US
PCT/EP2004/051661 29.07.2004 EP
PCT/EP2004/052286 23.09.2004 EP
PCT/EP2004/052772 03.11.2004 EP
PCT/EP2005/050310 25.01.2005 EP
PCT/EP2005/050953 03.03.2005 EP
Title (EN) BINDING MOLECULES CAPABLE OF NEUTRALIZING RABIES VIRUS AND USES THEREOF
(FR) MOLECULES DE LIAISON POUVANT NEUTRALISER LE VIRUS DE LA RAGE ET UTILISATION
Abstract: front page image
(EN)The present invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the postexposure prophylaxis of rabies.
(FR)La présente invention concerne des molécules de liaison spécifique au virus de la rage pouvant neutraliser le virus. L'invention concerne égalemennt des molécules d'acides nucléiques codant pour les molécules de liaison, des compositions contenant les molécules de liaison, et des méthodes d'identification ou de production des molécules de liaison. Les molécules de liaison peuvent être utilisées dans le diagnostic, la prophylaxie et/ou le traitement d'un état généré par le virus de la rage. Lesdites molécules peuvent être utilisées, de préférence, dans la prophylaxie de post-exposition à la rage.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)