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1. (WO2005118615) INHIBITORS OF REGIII PROTEINS AS ASTHMA THERAPEUTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118615    International Application No.:    PCT/US2005/019594
Publication Date: 15.12.2005 International Filing Date: 03.06.2005
IPC:
C07K 1/00 (2006.01), A61K 39/385 (2006.01), A61K 39/395 (2006.01)
Applicants: WYETH [US/US]; Five Giralda Farms, Madison, NJ 07940 (US) (For All Designated States Except US).
FOLLETTIE, Maximillian [US/US]; (US) (For US Only).
DONALDSON, Debra, D. [US/US]; (US) (For US Only)
Inventors: FOLLETTIE, Maximillian; (US).
DONALDSON, Debra, D.; (US)
Agent: EDWARDS, Mary, J.; Wilmer Cutler Pickering Hale and Dorr LLP, 60 State Street, Boston, MA 02109 (US)
Priority Data:
60/577,258 04.06.2004 US
Title (EN) INHIBITORS OF REGIII PROTEINS AS ASTHMA THERAPEUTICS
(FR) INHIBITEURS DE PROTEINES REGIII, AGENTS THERAPEUTIQUES CONTRE L'ASTHME
Abstract: front page image
(EN)Methods of screening for agents for treating asthma are provided. The methods involve screening for agents that decrease the production or activity of a RegIII protein that has been discovered herein to play a role in producing the symptoms and pathological complications involved in asthma. Methods of treating asthma, as well as screening for and treating with inhibitors of a RegIII protein are also provided.
(FR)L'invention porte sur des procédés de criblage d'agents de traitement de l'asthme. Lesdits procédés consistent à effectuer un criblage d'agents réduisant la production ou l'activité de la protéine RegIII dont l'invention a découvert qu'elle jouait un rôle dans la production des symptômes et complications pathologiques liées à l'asthme. L'invention porte également sur des procédés: de traitement de l'asthme, de criblage d'inhibiteurs de la protéine RegIII, et de traitement au moyen desdits inhibiteurs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)