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1. (WO2005118591) CONDENSED PIPERIDINE COMPOUNDS ACTING AS ADRENERGIC RECEPTOR ANTAGONISTS USEFUL IN THE TREATMENT OF PROSTATIC HYPERPLASIA AND LOWER URINARY SYMPTOMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118591    International Application No.:    PCT/IB2005/001464
Publication Date: 15.12.2005 International Filing Date: 26.05.2005
IPC:
C07D 487/14 (2006.01), A61K 31/4738 (2006.01)
Applicants: RANBAXY LABORATORIES LIMITED [IN/IN]; Plot No. 90, Sector-32, Gurgaon, Haryana 122001 (IN) (For All Designated States Except US).
ANAND, Nitya [IN/IN]; (IN) (For US Only).
SALMAN, Mohammad [IN/US]; (US) (For US Only).
YADAV, Gyan, Chand [IN/IN]; (IN) (For US Only).
SHARMA, Somesh [IN/IN]; (IN) (For US Only).
KAPKOTI, Gobind, Singh [IN/IN]; (IN) (For US Only).
CHUGH, Anita [IN/IN]; (IN) (For US Only).
NANDA, Kamna [IN/IN]; (IN) (For US Only)
Inventors: ANAND, Nitya; (IN).
SALMAN, Mohammad; (US).
YADAV, Gyan, Chand; (IN).
SHARMA, Somesh; (IN).
KAPKOTI, Gobind, Singh; (IN).
CHUGH, Anita; (IN).
NANDA, Kamna; (IN)
Common
Representative:
RANBAXY LABORATORIES LIMITED; c/o DESHMUKH, Jay R., 600 College Road East, Suite 2100, Princeton, NJ 08540 (US)
Priority Data:
991/DEL/2004 31.05.2004 IN
Title (EN) CONDENSED PIPERIDINE COMPOUNDS ACTING AS ADRENERGIC RECEPTOR ANTAGONISTS USEFUL IN THE TREATMENT OF PROSTATIC HYPERPLASIA AND LOWER URINARY SYMPTOMS
(FR) COMPOSES A BASE DE PIPERIDINES CONDENSES AGISSANT COMME ANTAGONISTES DES RECEPTEURS ADRENERGIQUES, UTILISES DANS LE TRAITEMENT DES SYMPTOMES LIES A L'HYPERPLASIE BENIGNE DE LA PROSTATE ET AUX VOIES URINAIRES INFERIEURES
Abstract: front page image
(EN)The present invention relates to &agr;1a and/or &agr;1d adrenergic receptor antagonists. Compounds provided herein can function as &agr;1a and/or &agr;1d adrenergic receptor antagonist and can be used for the treatment of a disease or disorder mediated through &agr;1a and/or &agr;1d adrenergic receptor. Compounds provided herein can be used for the treatment of benign prostatic hyperplasia (BPH) and the related symptoms thereof, lower urinary tract symptoms (LUTS) associated with or without BPH. Processes for the preparation of the provided compounds, as well as, pharmaceutical composition containing the provided compounds, and methods of treating benign prostatic hyperplasia or related symptoms thereof are provided herein.
(FR)La présente invention concerne des antagonistes des récepteurs adrénergiques $g(a)1a et/ou $g(a)1d. Les composés de la présente invention peuvent servir d'antagonistes des récepteurs adrénergiques $g(a)1a et/ou $g(a)1d et peuvent être utilisés pour le traitement d'une maladie ou d'un trouble induit par les récepteurs adrénergiques $g(a)1a et/ou $g(a)1d. Les composés de la présente invention peuvent être utilisés pour le traitement de l'hyperplasie bénigne de la prostate et de ses symptômes, ainsi que des symptômes des voies urinaires inférieures associés ou non à l'hyperplasie bénigne de la prostate. L'invention concerne également des procédés destinés à la préparation desdits composés, des compositions pharmaceutiques contenant lesdits composés, ainsi que des méthodes destinées au traitement de l'hyperplasie bénigne de la prostate ou de ses symptômes.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)