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1. (WO2005118579) THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118579    International Application No.:    PCT/GB2005/002142
Publication Date: 15.12.2005 International Filing Date: 31.05.2005
IPC:
C07D 417/12 (2006.01), C07D 417/14 (2006.01), A61K 31/427 (2006.01), A61P 11/06 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-SE-151 85 Sodertalje (SE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate, London Greater London W1K 1LN (GB) (MG only).
BOWER, Justin Fairfield [GB/GB]; (GB) (For US Only).
HAMLIN, Gordon Alexander [GB/GB]; (GB) (For US Only).
WINTER, Jon [GB/GB]; (GB) (For US Only)
Inventors: BOWER, Justin Fairfield; (GB).
HAMLIN, Gordon Alexander; (GB).
WINTER, Jon; (GB)
Agent: ASTRAZENECA; Global Intellectual Property, S-151 85 Sodertalje (SE)
Priority Data:
0412468.1 04.06.2004 GB
Title (EN) THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS
(FR) COMPOSES CHIMIQUES
Abstract: front page image
(EN)The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R1, Ra, R8, R2, R3 and R4 are as defined in the specification, in the preparation of a medicament for the treatment of C-C chemokine mediated conditions. Novel compounds of formula (I) and pharmaceutical compositions containing them are also described and claimed.
(FR)L'invention concerne l'utilisation d'un composé représenté par la formule générale (I) ou d'un de ses sels ou solvates de qualité pharmaceutique, dans la préparation d'un médicament destiné au traitement de troubles induits par la chimiokine CC. Dans cette formule, R1, Ra, R8, R2, R3 et R4 désignent des éléments définis dans la description de la présente demande. L'invention concerne également de nouveaux composés représentés par la formule générale (I) et des compositions pharmaceutiques contenant ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)