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Machine translation
1. (WO2005118570) BUTYRYLCHOLINESTERASE SELECTIVE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118570    International Application No.:    PCT/EP2005/005816
Publication Date: 15.12.2005 International Filing Date: 27.05.2005
IPC:
C07D 401/12 (2006.01), A61K 31/454 (2006.01), A61P 25/28 (2006.01)
Applicants: NEUROPHARMA, S.A. [ES/ES]; Avenida de la Industria, 52, E-28760 Tres Cantos - Madrid (ES) (For All Designated States Except US).
MARTÍNEZ GIL, Ana [ES/ES]; (ES) (For US Only).
RUBIO ARRIETA, Laura [ES/ES]; (ES) (For US Only).
MUÑOZ RUÍZ, Pilar [ES/ES]; (ES) (For US Only).
DORRONSORO DÍAZ, Isabel [ES/ES]; (ES) (For US Only).
GARCÍA PALOMERO, Esther [ES/ES]; (ES) (For US Only).
DEL MONTE MILLÁN, María [ES/ES]; (ES) (For US Only).
MEDINA PADILLA, Miguel [ES/ES]; (ES) (For US Only)
Inventors: MARTÍNEZ GIL, Ana; (ES).
RUBIO ARRIETA, Laura; (ES).
MUÑOZ RUÍZ, Pilar; (ES).
DORRONSORO DÍAZ, Isabel; (ES).
GARCÍA PALOMERO, Esther; (ES).
DEL MONTE MILLÁN, María; (ES).
MEDINA PADILLA, Miguel; (ES)
Agent: BERNARDO NORIEGA, Francisco; ABG Patentes, S.L., Orense, 68 7th floor, E-28020 Madrid (ES)
Priority Data:
04076585.1 28.05.2004 EP
Title (EN) BUTYRYLCHOLINESTERASE SELECTIVE INHIBITORS
(FR) INHIBITEURS SELECTIFS DE BUTYRYLCHOLINESTERASE
Abstract: front page image
(EN)The invention provides butyrylcholinesterase inhibitors of formula (I), which contain an heterocyclic moiety and a 4 piperidine moiety with a linker in between. The compounds show a very high activity and selectivity towards BuChE, making them useful for the treatment and/or prophylaxis of cognitive disorders and/or neurodegenerative disorders.
(FR)L'invention concerne des inhibiteurs de butyrylcholinestérase de formule (I), renfermant une fraction hétérocyclique et une fraction de 4 pipéridine reliées par un élément de liaison. Ces composés assurent une activité et une sélectivité soutenues vis-à-vis de BuChE, ce qui les rend utiles pour le traitement et/ou la prévention des troubles cognitifs et/ou neurodégénératifs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)