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Machine translation
1. (WO2005118511) COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/118511    International Application No.:    PCT/US2005/019184
Publication Date: 15.12.2005 International Filing Date: 20.05.2005
IPC:
C07C 39/15 (2006.01), C07C 59/68 (2006.01), C07C 65/05 (2006.01), C07C 229/48 (2006.01), C07C 229/58 (2006.01), C07C 251/52 (2006.01), C07C 251/60 (2006.01), A61K 31/15 (2006.01), A61K 31/192 (2006.01), A61K 31/196 (2006.01), A61K 31/60 (2006.01), A61P 3/04 (2006.01), A61P 25/28 (2006.01)
Applicants: THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10666 North Torrey Pines Road, La Jolla, CA 92037 (US) (For All Designated States Except US).
KELLY, Jeffrey, W. [US/US]; (US) (For US Only)
Inventors: KELLY, Jeffrey, W.; (US)
Agent: RIEGER, Dale L.K.; JONES DAY, 222 East 41th Street, New York, NY 10017-6702 (US)
Priority Data:
60/573,720 20.05.2004 US
Title (EN) COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING
(FR) COMPOSES, COMPOSITIONS ET METHODES PERMETTANT DE STABILISER LA TRANSTHYRETINE ET D'INHIBER UN MAUVAIS REPLIEMENT DE LA TRANSTHYRETINE
Abstract: front page image
(EN)Compounds, compositions and methods are provided for stabilizing transthyretin and for treating, preventing, or ameliorating one or more symptoms of transthyretin mediated diseases. In one embodiment, the compounds are biphenyls and related compounds.
(FR)L'invention concerne des composés, des compositions et des méthodes de stabilisation de transthyrétine et de traitement, de prévention ou d'amélioration d'un ou de plusieurs symptômes de maladies médiées par la transthyrétine. Dans un mode de réalisation, les composés sont des biphényles et des composés associés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)