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1. (WO2005117999) IMAGING AND THERAPEUTIC AGENTS TARGETING PROTEINS EXPRESSED ON ENDOTHELIAL CELL SURFACE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/117999 International Application No.: PCT/US2005/019538
Publication Date: 15.12.2005 International Filing Date: 02.06.2005
IPC:
A61K 51/08 (2006.01) ,A61K 51/10 (2006.01) ,A61P 35/00 (2006.01) ,A61K 47/48 (2006.01)
Applicants: SCHNITZER, Jan, E.[US/US]; US (UsOnly)
OH, Philip[US/US]; US (UsOnly)
SIDNEY KIMMEL CANCER CENTER[US/US]; 10835 Altman Row San Diego, CA 92121, US (AllExceptUS)
Inventors: SCHNITZER, Jan, E.; US
OH, Philip; US
Agent: HOGLE, Doreen, M. ; Hamilton, Brook, Smith & Reynolds, P.C. 530 Virginia Road P.O. Box 9133 Concord, MA 01742-9133, US
Priority Data:
60/576,19202.06.2004US
Title (EN) IMAGING AND THERAPEUTIC AGENTS TARGETING PROTEINS EXPRESSED ON ENDOTHELIAL CELL SURFACE
(FR) IMAGERIE ET CIBLAGE D'AGENTS THERAPEUTIQUES DE PROTEINES EXPRIMEES SUR LA SURFACE D'UNE CELLULE ENDOTHELIALE
Abstract:
(EN) Methods of delivering an agent in a tissue-specific manner, by targeting proteins expressed on endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy.
(FR) Des procédés d'administration d'un agent d'une manière spécifique au tissu par ciblage des protéines exprimées sur la surface d'une cellule endothéliale. Les procédés peuvent servir à détecter, imager et/ou traiter une tumeur, une angiogenèse ou une néovascularisation, ainsi qu'à diagnostique et mettre en oeuvre des procédés d'évaluation de l'efficacité d'un traitement.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)