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Machine translation
1. (WO2005117946) TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/117946    International Application No.:    PCT/EP2005/052430
Publication Date: 15.12.2005 International Filing Date: 27.05.2005
IPC:
A61K 38/18 (2006.01), A61P 9/00 (2006.01), A61P 25/14 (2006.01)
Applicants: VIB vzw [BE/BE]; Rijvisschestraat 120, B-9052 Zwijnaarde (BE) (For All Designated States Except US).
D. COLLEN RESEARCH FOUNDATION VZW [BE/BE]; Onderwijs & Navorsing, Campus Gasthuisbe, K.U. Leuven, Herestraat 49, B-3000 Leuven (BE) (For All Designated States Except US).
CARMELIET, Peter [BE/BE]; (BE) (For US Only)
Inventors: CARMELIET, Peter; (BE)
Common
Representative:
VIB vzw; Rijvisschestraat 120, B-9052 Zwijnaarde (BE)
Priority Data:
04102334.2 27.05.2004 EP
Title (EN) TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
(FR) TRAITEMENT DE LA SCLEROSE LATERALE AMYOTROPHIQUE
Abstract: front page image
(EN)The present invention relates to the treatment of motoneuron diseases. More particularly the invention relates to the treatment of amyotrophic lateral sclerosis (ALS). It is found that the intracerebroventricular delivery of low amounts of vascular endothelial growth factor into a preclinical ALS animal model induces a significant motor performance and prolongation of survival time of said animals.
(FR)L'invention concerne un traitement de maladies des motoneurones. En particulier, l'invention concerne le traitement de la sclérose latérale amyotrophique (SLA). Dans l'invention, on a découvert que l'administration intracérébroventriculaire de faibles quantités d'un facteur de croissance endothéliale vasculaire dans un modèle animal SLA préclinique induit une performance moteur et une prolongation significatives de la durée de vie des animaux ayant subi ce traitement.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)