WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005117514) METHOD OF DETECTING CYSTIC FIBROSIS ASSOCIATED MUTATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/117514    International Application No.:    PCT/CA2005/000829
Publication Date: 15.12.2005 International Filing Date: 01.06.2005
Chapter 2 Demand Filed:    12.01.2006    
IPC:
C12Q 1/68 (2006.01)
Applicants: TM BIOSCIENCE CORPORATION [CA/CA]; Suite 900, 439 University Avenue, Toronto, Ontario M5G 1Y8 (CA) (For All Designated States Except US).
GALVAN, Barbara [CA/CA]; (CA) (For US Only).
LISLE, Connie [--/CA]; (CA) (For US Only)
Inventors: GALVAN, Barbara; (CA).
LISLE, Connie; (CA)
Agent: GRAVELLE, Micheline; Bereskin & Parr, 40 King street West, Suite 4000, Toronto, Ontario M5H 3Y2 (CA)
Priority Data:
60/575,394 01.06.2004 US
Title (EN) METHOD OF DETECTING CYSTIC FIBROSIS ASSOCIATED MUTATIONS
(FR) PROCÉDÉ DE DÉTECTION DES MUTATIONS ASSOCIÉES À LA FIBROSE CYSTIQUE
Abstract: front page image
(EN)The present invention describes a method for the simultaneous identification of two or more single base changes, insertions, deletions or translocations in a plurality of target nucleotide sequences that are markers associated with cystic fibrosis. Multiplex detection is accomplished using multiplexed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support.
(FR)La présente invention décrit un procédé d’identification simultanée de deux modifications, insertions, suppressions ou translocations, ou plus, de bases simples dans une pluralité de séquences nucléotidiques cibles qui sont des marqueurs associés à la fibrose cystique. La détection multiplex est effectuée en utilisant une extension d’amorces allèle-spécifiques (ASPE) marquée multiplexée et l’hybridation de ces amorces allongées en une sonde, de préférence un support anti-marqué adressable.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)