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1. (WO2005116234) DETECTION AND QUANTIFICATION OF INTRACELLULAR PATHOGENS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/116234    International Application No.:    PCT/US2005/012660
Publication Date: 08.12.2005 International Filing Date: 15.04.2005
IPC:
G01N 33/53 (2006.01), G01N 33/571 (2006.01), G01N 1/30 (2006.01)
Applicants: UNIVERSITY OF MASSACHUSETTS [US/US]; One Beacon Street, 26th Floor, Boston, MA 02108 (US) (For All Designated States Except US).
SEMPREVIVO, Lloyd, H. [US/US]; (US) (For US Only).
STUART, Elizabeth, S. [US/US]; (US) (For US Only)
Inventors: SEMPREVIVO, Lloyd, H.; (US).
STUART, Elizabeth, S.; (US)
Agent: FASSE, J., Peter; Fish & Richardson P.C., 225 Franklin Street, Boston, MA 02110-2804 (US)
Priority Data:
60/563,087 16.04.2004 US
Title (EN) DETECTION AND QUANTIFICATION OF INTRACELLULAR PATHOGENS
(FR) DÉTECTION ET QUANTIFICATION D'AGENTS PATHOGÈNES INTRACELLULAIRES
Abstract: front page image
(EN)The present invention provides methods and compositions for detecting bacteria of the Chlamydiaceae family in a biological sample. Methods include, for example, contacting a biological sample with an antibody that specifically binds to a chlamydial antigen displayed on the surface of a chlamydia-infected blood cell; and analyzing the sample using fluorescence microscopy or flow cytometry to detect bound antibody.
(FR)La présente invention fournit des procédés et des compositions destinés à détecter des bactéries de la famille Chlamydiaceae dans un échantillon biologique. Les procédés comprennent, par exemple, la mise en contact d'un échantillon biologique avec un anticorps qui se lie spécifiquement à un antigène qui se rapporte aux Chlamydia montrées à la surface d'une cellule sanguine infectée par les Chlamydia, ainsi que l'analyse de l'échantillon en utilisant la microscopie par fluorescence ou la cytométrie par écoulement afin de détecter un anticorps lié.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)