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1. (WO2005116205) MARKER GENES FOR JUDGING PACLITAXEL-SENSITIVITY AND JUDGMENT METHOD
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/116205    International Application No.:    PCT/JP2004/007574
Publication Date: 08.12.2005 International Filing Date: 26.05.2004
Chapter 2 Demand Filed:    16.11.2004    
IPC:
C12N 15/09 (2006.01), C12Q 1/68 (2006.01), G01N 33/15 (2006.01), G01N 33/50 (2006.01)
Applicants: YOSHIMOTO, Masataka [JP/JP]; (JP).
JAPANESE FOUNDATION FOR CANCER RESEARCH [JP/JP]; 37-1, Kami-ikebukuro 1-chome Toshima-ku, Tokyo 1708455 (JP) (For All Designated States Except US).
JAPAN BIOLOGICAL INFORMATICS CONSORTIUM [JP/JP]; Grandebuilding 26-9, Hacchobori 2-chome Chuo-ku, Tokyo 1040032 (JP) (For All Designated States Except US).
MIKI, Yoshio [JP/JP]; (JP) (For US Only).
NODA, Tetsuo [JP/JP]; (JP) (For US Only).
MATSUURA, Masaaki [JP/JP]; (JP) (For US Only)
Inventors: YOSHIMOTO, Masataka; (JP).
MIKI, Yoshio; (JP).
NODA, Tetsuo; (JP).
MATSUURA, Masaaki; (JP)
Agent: HIRAKI, Yusuke; Kamiya-cho MT Bldg. 19F 3-20, Toranomon 4-chome Minato-ku, Tokyo 1050001 (JP)
Priority Data:
Title (EN) MARKER GENES FOR JUDGING PACLITAXEL-SENSITIVITY AND JUDGMENT METHOD
(FR) GÈNES MARQUEURS POUR ESTIMER LA SENSIBILITÉ AU PACLITAXEL ET PROCÉDÉ DE JUGEMENT
(JA) パクリタキセルに対する感受性判定マーカー遺伝子および判定方法
Abstract: front page image
(EN)It is intended to provide a means of judging the sensitivity to paclitaxel of a patient with breast cancer. A marker gene for judging the sensitivity to the paclitaxel of a patient with breast cancer which is selected from genes comprising the base sequences represented by SEQ ID NOS:1 to 66; a method of judging the sensitivity to the paclitaxel of a patient with breast cancer based on the expression amount of the marker; an oligonucleotide for analyzing the expression amount of the marker gene; and a kit containing the same.
(FR)Il est prévu de fournir un moyen pour estimer la sensibilité au paclitaxel d'un patient souffrant du cancer du sein. Un gène marqueur pour estimer la sensibilité au paclitaxel d'un patient avec le cancer du sein qui est sélectionné parmi les gènes comprenant les séquences de base représentées par SEQ ID NOS:1 à 66; un procédé de sensibilité au paclitaxel d'un patient avec le cancer du sein basé sur la quantité d'expression du marqueur, un oligonucléotide pour analyser la quantité d'expression du gène marqueur et un kit contenant ce dernier.
(JA)本発明は、乳癌患者のパクリタキセルに対する感受性を判定するための手段を提供することを目的とする。 本発明は、配列番号1~66に示す塩基配列からなる遺伝子から選択される、乳癌患者のパクリタキセルに対する感受性判定マーカー遺伝子、該マーカーの発現量に基づいて乳癌患者のパクリタキセルに対する感受性を判定する方法、該マーカー遺伝子の発現量を解析するためのオリゴグヌクレオチド、それを含むキットに関する。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)