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Machine translation
1. (WO2005115306) KERATIN-BINDING POLYPEPTIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/115306    International Application No.:    PCT/EP2005/005599
Publication Date: 08.12.2005 International Filing Date: 24.05.2005
IPC:
A61K 8/64 (2006.01), A61Q 3/00 (2006.01), A61Q 5/12 (2006.01), A61Q 19/00 (2006.01)
Applicants: BASF AKTIENGESELLSCHAFT [DE/DE]; 67056 Ludwigshafen (DE) (For All Designated States Except US).
BARG, Heiko [DE/DE]; (DE) (For US Only).
SUBKOWSKI, Thomas [DE/DE]; (DE) (For US Only).
LEMAIRE, Hans-Georg [DE/DE]; (DE) (For US Only).
BOLLSCHWEILER, Claus [DE/DE]; (DE) (For US Only).
PTOCK, Arne [DE/DE]; (DE) (For US Only)
Inventors: BARG, Heiko; (DE).
SUBKOWSKI, Thomas; (DE).
LEMAIRE, Hans-Georg; (DE).
BOLLSCHWEILER, Claus; (DE).
PTOCK, Arne; (DE)
Common
Representative:
BASF AKTIENGESELLSCHAFT; 67056 Ludwigshafen (DE)
Priority Data:
102004025805.8 24.05.2004 DE
102005011988.3 14.03.2005 DE
Title (DE) KERATIN-BINDENDE POLYPEPTIDE
(EN) KERATIN-BINDING POLYPEPTIDES
(FR) POLYPEPTIDE LIANT LA KERATINE
Abstract: front page image
(DE)Die vorliegende Erfindung betrifft neue Keratin-bindende Proteinwirkstoffe, ihre Herstellung und Verwendung. Besonders gut geeignete Keratin-bindende Polypeptide sind solche Sequenzen, die im humanen Desmoplakinpolypeptidsequenzen wie Aminosäure-Insertionen, -Substitutionen oder -Deletionen daraus abgeleitet wird. Die Polypeptidsequenz des humanen Desmoplakins ist SEQ ID NO:1 dargestellt. Eine geeignete Keratin-bindende Domäne (Domäne B) ist die Polypeptidsequenz SEQ ID NO:1 Position 2193 bis 2481 sowie deren funktionelle Äquivalente. Eine weitere Keratin-bindende Domäne (Domäne C) ist die Polypeptidsequenz SEQ ID NO:1 Position 2606 bis 2871 sowie deren funktionelle Äquivalente.
(EN)The invention relates to novel keratin-binding protein active substances, and also to the production and use thereof. Particularly suitable keratin-binding polypeptides are sequences which are contained in human desmoplakin or are derived therefrom by altering the human desmoplakin polypeptide sequences such as amino acid insertions, substitutions or deletions. The polypeptide sequences of the human desmoplakin is represented in SEQ ID NO: 1. A suitable keratin-binding domain (domain B) is the polypeptide sequence SEQ ID NO: 1, position 2193 2481, in addition to functional equivalents thereof. An additional keratin-binding domain (domain C) is the polypeptide sequence SEQ ID NO: 1, position 2606 2871 and the functional equivalents thereof.
(FR)L'invention concerne de nouvelles substances actives de protéine liant la kératine, leur fabrication et leur utilisation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)