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1. (WO2005114206) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH SEROTONIN 5-HT5A RECEPTOR (5HT5A)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/114206    International Application No.:    PCT/EP2005/004725
Publication Date: 01.12.2005 International Filing Date: 30.04.2005
IPC:
G01N 33/94 (2006.01), C12Q 1/68 (2006.01), C07K 14/705 (2006.01), G01N 33/574 (2006.01), G01N 33/68 (2006.01), A61K 39/395 (2006.01), A61K 38/45 (2006.01), A61K 47/46 (2006.01), A61K 31/70 (2006.01), A61P 1/00 (2006.01), A61P 3/00 (2006.01), A61P 29/00 (2006.01), A61P 31/00 (2006.01), A61P 33/00 (2006.01), A61P 35/00 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
GEERTS, Andreas [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
GEERTS, Andreas; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
04011362.3 13.05.2004 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH SEROTONIN 5-HT5A RECEPTOR (5HT5A)
(FR) DIAGNOSTIC ET TRAITEMENT THERAPEUTIQUE DE MALADIES ASSOCIEES AU RECEPTEUR DE LA SEROTONINE 5-HT5A (5HT5A)
Abstract: front page image
(EN)The invention provides a human 5HT5a which is associated with the cardiovascular diseases, infections, gastroenterological diseases, cancer, inflammation, metabolic diseases, hematological diseases, neurological diseases, urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, infections, gastroenterological diseases, cancer, inflammation, metabolic diseases, hematological diseases, neurological diseases, urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of 5HT5a as well as pharmaceutical compositions comprising such compounds.
(FR)L'invention concerne un 5HT5a humain associé aux maladies cardiovasculaires, aux infections, aux maladies gastroentérologiques, au cancer, à l'inflammation, aux maladies métaboliques, aux maladies hématologiques, aux maladies neurologiques et aux maladies urologiques. L'invention concerne également des dosages permettant d'identifier des composés utilisés dans le traitement ou la prévention des maladies cardiovasculaires, des infections, des maladies gastroentérologiques, du cancer, de l'inflammation, des maladies métaboliques, des maladies hématologiques, des maladies neurologiques et des maladies urologiques. L'invention concerne également des composés de liaison et/ou d'activation ou d'inhibition de l'activité du 5HT5a, ainsi que des compositions pharmaceutiques contenant lesdits composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)