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1. (WO2005114201) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR NPY2 (NPY2)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/114201    International Application No.:    PCT/EP2005/004903
Publication Date: 01.12.2005 International Filing Date: 06.05.2005
IPC:
G01N 33/574 (2006.01), G01N 33/68 (2006.01), G01N 33/566 (2006.01), G01N 33/50 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
GEERTS, Andreas [DE/DE]; (DE) (For US Only).
SUMMER, Holger [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
GEERTS, Andreas; (DE).
SUMMER, Holger; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
04012026.3 21.05.2004 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR NPY2 (NPY2)
(FR) AGENTS THERAPEUTIQUES ET DIAGNOSTIQUES POUR DES MALADIES ASSOCIEES AU RECEPTEUR NPY2 (NPY2) COUPLE A LA PROTEINE G
Abstract: front page image
(EN)The invention provides a human NPY2 which is associated with the cardiovascular disorders, gastrointestinal and liver diseases, metabolic diseases, inflammatory diseases, hematological disorders, respiratory diseases, muscle-skeleton disorders, neurological disorders, reproduction disorders, cancer disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, gastrointestinal and liver diseases, metabolic diseases, inflammatory diseases, hematological disorders, respiratory diseases, muscle-skeleton disorders, neurological disorders, reproduction disorders, cancer disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of NPY2 as well as pharmaceutical compositions comprising such compounds.
(FR)L'invention concerne un NPY2 humain qui est associé aux troubles cardiovasculaires, aux maladies gastrointestinales et hépatiques, aux dysfonctionnements hématologiques, aux maladies respiratoires, aux troubles musculo-squelettiques, aux troubles neurologiques, aux troubles reproductifs, aux troubles cancéreux et aux troubles urologiques. L'invention porte également sur des essais pour l'identification de composés utiles dans le traitement ou la prévention de troubles cardio-vasculaires, de maladies gastro-intestinales et hépatiques, de maladies métaboliques, de maladies inflammatoires, de troubles hématologiques, de maladies respiratoires, de troubles musculo-squelettiques, de troubles neurologiques, de troubles de la reproduction, de troubles cancéreux et de troubles urologiques. L'invention porte également sur des composés qui le lient à NPY et/ou activent ou inhibent son activité, ainsi que sur des compositions pharmaceutiques comprenant lesdits composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)