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Machine translation
1. (WO2005114189) METHODS OF DIAGNOSING INFLAMMATORY BOWEL DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/114189    International Application No.:    PCT/US2005/016965
Publication Date: 01.12.2005 International Filing Date: 12.05.2005
Chapter 2 Demand Filed:    13.12.2005    
IPC:
G01N 33/53 (2006.01), G01N 33/567 (2006.01)
Applicants: PROMETHEUS LABORATORIES INC. [US/US]; 5739 Pacific Center Blvd., San Diego, CA 92121 (US) (For All Designated States Except US).
OH, Esther, H. [US/US]; (US) (For US Only).
MARCELLETTI, John, F. [US/US]; (US) (For US Only).
CARROLL, Susan, M. [US/US]; (US) (For US Only).
SMITH, Katie, M. [US/US]; (US) (For US Only)
Inventors: OH, Esther, H.; (US).
MARCELLETTI, John, F.; (US).
CARROLL, Susan, M.; (US).
SMITH, Katie, M.; (US)
Agent: SNYDER, Joseph, R.; Townsend and Townsend and Crew LLP, Two Embarcadero Center, 8th Floor, San Francisco, CA 94111 (US)
Priority Data:
60/571,216 13.05.2004 US
11/128,011 11.05.2005 US
Title (EN) METHODS OF DIAGNOSING INFLAMMATORY BOWEL DISEASE
(FR) METHODES DE DIAGNOSTIC DE LA MALADIE INTESTINALE INFLAMMATOIRE
Abstract: front page image
(EN)The present invention provides methods for diagnosing the presence or severity of inflammatory bowel disease (IBD) in an individual and methods for stratifying IBD by determining the level of one or more IBD markers in a sample from the individual and calculating an index value using an algorithm based upon the level of the IBD markers. Methods for monitoring the efficacy of IBD therapy, monitoring the progression or regression of IBD, and optimizing therapy in an individual having IBD are also provided.
(FR)La présente invention concerne des méthodes de diagnostic de la présence ou de la gravité de la maladie intestinale inflammatoire (MII) chez un individu et des méthodes de classification par stades de la MII par détermination du niveau d'au moins un marqueur MII dans un échantillon provenant de l'individu et par le calcul d'une valeur d'indice au moyen d'un algorithme fondé sur le niveau des marqueurs MII. Cette invention concerne également des méthodes de surveillance de l'efficacité de la thérapie MII, de surveillance de la progression ou de la régression de MII et d'optimisation de la thérapie chez un individu souffrant d'une MII.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)