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1. (WO2005113800) METHOD AND DEVICE FOR MONITORING ASPIRIN RESPONSE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/113800    International Application No.:    PCT/US2005/016882
Publication Date: 01.12.2005 International Filing Date: 14.05.2005
IPC:
C12Q 1/66 (2006.01)
Applicants: MEDICAL INNOVATIONS INTERNATIONAL, INC. [US/US]; 6256 34th Ave. NW, Rochester, MN 55901 (US) (For All Designated States Except US).
ERICSON, Daniel, G. [US/US]; (US) (For US Only)
Inventors: ERICSON, Daniel, G.; (US)
Priority Data:
10/846,439 14.05.2004 US
Title (EN) METHOD AND DEVICE FOR MONITORING ASPIRIN RESPONSE
(FR) PROCEDE ET DISPOSITIF DE SURVEILLANCE DE LA REPONSE A L'ASPIRINE
Abstract: front page image
(EN)The invention provides a method of monitoring the response of platelets to a COX1 inhibitor such as aspirin. The method involves collecting platelet-containing mammalian blood treated with a COX 1 inhibitor; mixing the blood with a COX 1-dependent platelet agonist, such as arachidonic acid, monitoring extracellular ATP in the agonist-activated bl>>d to generate a measurement, and comparing the measurement to a standard value. Devices, systems, and kits for carrying out the method are also provided.
(FR)La présente invention concerne un procédé de surveillance de la réponse des plaquettes à un inhibiteur COX1 tel que l'aspirine. Le procédé implique de collecter du sang de mammifère contenant des plaquettes qui a été traité avec un inhibiteur COX1; de mélanger le sang avec un agoniste dépendant des plaquettes COX1, tel que l'acide arachidonique, de surveiller l'ATP extracellulaire dans le sang activé par l'agoniste pour générer une mesure, et de comparer la mesure à une valeur standard. Cette invention concerne également des dispositifs, des systèmes et des trousses utiles pour mettre en oeuvre le procédé.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)