WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005113764) MODULATION OF WRN-MEDIATED TELOMERE-INITIATED CELL SIGNALING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/113764    International Application No.:    PCT/US2005/017553
Publication Date: 01.12.2005 International Filing Date: 19.05.2005
IPC:
C12N 9/14 (2006.01)
Applicants: TRUSTEES OF BOSTON UNIVERSITY [US/US]; One Sherborn Street, Boston, MA 02215 (US) (For All Designated States Except US).
GILCHREST, Barbara, A. [US/US]; (US) (For US Only).
ELLER, Mark, S. [US/US]; (US) (For US Only)
Inventors: GILCHREST, Barbara, A.; (US).
ELLER, Mark, S.; (US)
Agent: SCOTT, Teddy, C., Jr.; Howrey LLP, 2941 Farview Park Drive, Box 7, Falls Church, VA 22042 (US)
Priority Data:
60/572,625 19.05.2004 US
Title (EN) MODULATION OF WRN-MEDIATED TELOMERE-INITIATED CELL SIGNALING
(FR) MODULATION DE SIGNALISATION CELLULAIRE INITIEE PAR TELOMERE MEDIE PAR WRN
Abstract: front page image
(EN)The use of modulators of WRN is described. Activators of WRN may be used to induce growth arrest, apoptosis or proliferative senescence, whereas inhibitors of WRN may be used to reduce growth arrest, apoptosis or prolifertative senescence. Methods of identifying modulators of WRN are also described.
(FR)L'invention concerne l'utilisation de modulateurs de WRN. On peut utiliser des activateurs de WRN pour induire l'interruption de croissance, l'apoptose ou la sénescence proliférative, tandis que l'on peut utiliser des inhibiteurs de WRN pour réduire l'interruption de croissance, l'apoptose ou la sénescence proliférative. L'invention concerne également des procédés permettant d'identifier des modulateurs de WRN.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)