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Machine translation
1. (WO2005113560) THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AS PROTEIN KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/113560    International Application No.:    PCT/US2005/016150
Publication Date: 01.12.2005 International Filing Date: 10.05.2005
IPC:
C07D 495/04 (2006.01), A61K 31/4365 (2006.01)
Applicants: WYETH [US/US]; Five Giralda Farms, Madison, NJ 07940 (US) (For All Designated States Except US).
BOSCHELLI, Diane, Harris [US/US]; (US) (For US Only).
ZHANG, Nan [CN/US]; (US) (For US Only).
BARRIOS SOSA, Ana, Carolina [GT/US]; (US) (For US Only).
DURUTLIC, Haris [US/US]; (US) (For US Only).
WU, Biqi [US/US]; (US) (For US Only)
Inventors: BOSCHELLI, Diane, Harris; (US).
ZHANG, Nan; (US).
BARRIOS SOSA, Ana, Carolina; (US).
DURUTLIC, Haris; (US).
WU, Biqi; (US)
Agent: NESLER, Michael, J.; Wyeth, Patent Law Department, Five Giralda Farms, Madison, NJ 07940 (US)
Priority Data:
10/845,710 14.05.2004 US
Title (EN) THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AS PROTEIN KINASE INHIBITORS
(FR) THIENO[3,2-B]PYRIDINE-6-CARBONITRILES UTILISES EN TANT QU'INHIBITEURS DE LA PROTEINE KINASE
Abstract: front page image
(EN)This invention provides compounds of Formula II: wherein: R1, R2 and X are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection. The invention also provides processes for producing said compounds.
(FR)L'invention concerne des composés représentés par la formule II, dans laquelle R1, R2 et X sont définis dans le descriptif. Ces composés sont utiles dans le traitement du cancer, de l'apoplexie, de l'infarctus du myocarde, de la douleur neuropathique, de l'ostéoporose, de la maladie polykystique des reins, des maladies auto-immunes, de la polyarthrite rhumatoïde et d'un rejet de greffe. L'invention concerne également des procédés permettant de produire ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)