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Machine translation
1. (WO2005113013) COMPOSITIONS OF NDV AND METHODS OF USE THEREOF FOR TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/113013    International Application No.:    PCT/IL2005/000518
Publication Date: 01.12.2005 International Filing Date: 19.05.2005
IPC:
A61K 35/00 (2006.01), A61K 48/00 (2006.01), C12N 15/00 (2006.01), C12N 7/00 (2006.01)
Applicants: THERAVIR MANAGEMENT L.P. [IL/IL]; P.O. Box 12247, Jerusalem 91121 (IL) (For All Designated States Except US).
ZAKAY-RONES, Zichria [IL/IL]; (IL) (For US Only).
PANET, Amos [IL/IL]; (IL) (For US Only).
GREENBAUM, Evgeniya [RU/IL]; (IL) (For US Only).
GALUN, Eithan [IL/IL]; (IL) (For US Only).
FREEMAN, Arnold, I. [IL/IL]; (IL) (For US Only).
RASOOLY, Linda [IL/IL]; (IL) (For US Only).
IRVING, Charles, S. [US/IL]; (IL) (For US Only)
Inventors: ZAKAY-RONES, Zichria; (IL).
PANET, Amos; (IL).
GREENBAUM, Evgeniya; (IL).
GALUN, Eithan; (IL).
FREEMAN, Arnold, I.; (IL).
RASOOLY, Linda; (IL).
IRVING, Charles, S.; (IL)
Agent: WEBB, Cynthia; Webb & Associates, P.O. Box 2189, Rehovot 76121 (IL)
Priority Data:
60/572,475 20.05.2004 US
Title (EN) COMPOSITIONS OF NDV AND METHODS OF USE THEREOF FOR TREATMENT OF CANCER
(FR) COMPOSITIONS DE VMN ET METHODES D'UTILISATION DE CES COMPOSITIONS POUR LE TRAITEMENT DU CANCER
Abstract: front page image
(EN)The present invention discloses methods for inducing regression of a tumor in a subject comprising administering a pharmaceutical composition comprising a lentogenic strain of Newcastle disease virus (NDV). A preferred viral strain of NDV for inducing regression of a tumor in a subject is a clonal strain of NDV, the NDV HUJ. The methods of the present invention are particularly useful for inducing regression of tumors in patients unresponsive to conventional anti-cancer therapies.
(FR)La présente invention concerne des méthodes destinées à induire la régression d'une tumeur chez un sujet, qui consistent à administrer audit sujet une composition pharmaceutique comprenant une souche lentogène du virus de la maladie de Newcastle (VMN). Une souche virale de VMN préférée pouvant induire la régression d'une tumeur chez un sujet est une souche clonale de VMN appelée HUJ. Les méthodes de l'invention sont particulièrement utiles pour induire la régression de tumeurs chez des patients insensibles aux traitements classiques contre le cancer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)