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Machine translation
1. (WO2005113012) BETA ADRENERGIC DRUG CONJUGATED TO BONE TARGETING MOIETY FOR MODULATING BONE MASS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/113012    International Application No.:    PCT/US2005/016929
Publication Date: 01.12.2005 International Filing Date: 13.05.2005
IPC:
A61K 47/48 (2006.01), A61K 31/138 (2006.01), A61K 31/165 (2006.01), A61K 31/5377 (2006.01), A61P 19/10 (2006.01), A61P 19/08 (2006.01)
Applicants: BAYLOR COLLEGE OF MEDICINE [US/US]; Texas Medical Center, One Baylor Plaza, Houston, TX 77030 (US) (For All Designated States Except US).
KARSENTY, Gerard [FR/US]; (US) (For US Only).
DEVENS, Bruce [US/US]; (US) (For US Only)
Inventors: KARSENTY, Gerard; (US).
DEVENS, Bruce; (US)
Agent: FOX, Jim; HELLER EHRMAN LLP, 275 Middlefield Road, Menlo Park, CA 94025-3506 (US)
Priority Data:
60/571,558 14.05.2004 US
Title (EN) BETA ADRENERGIC DRUG CONJUGATED TO BONE TARGETING MOIETY FOR MODULATING BONE MASS
(FR) COMPOSITIONS ET PROCEDES POUR MODULER LA MASSE OSSEUSE
Abstract: front page image
(EN)The instant invention relates to compositions and methods for treating or preventing bone diseases. In certain aspects, the invention provides compositions comprising a &bgr;-adrenergic antagonist or agonist associated to a bone-targeted molecule, as well as methods of modulating bone mass and/or growth in a mammal by administering a composition of the present invention. In other aspects, the invention provides methods of modulating bone mass and/or growth in a mammal by administering a composition comprising a &bgr;2-selective antagonist or agonist.
(FR)Cette invention concerne des compositions et des procédés pour traiter ou prévenir les maladies osseuses. Dans certains de ses aspects, cette invention concerne des compositions comprenant un antagoniste ou un agoniste $g(b)-adrénergique associé à une molécule de ciblage osseux, ainsi que des procédés pour moduler la masse et/ou la croissance osseuse chez un mammifère, en lui administrant une telle composition. Dans d'autres aspects, cette invention concerne des procédés pour moduler la masse et/ou la croissance osseuse chez un mammifère en lui administrant une composition comprenant un antagoniste ou un agoniste $g(b)-adrénergique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)