WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005110963) (BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/110963    International Application No.:    PCT/EP2005/005444
Publication Date: 24.11.2005 International Filing Date: 19.05.2005
Chapter 2 Demand Filed:    20.03.2006    
IPC:
C07C 57/58 (2006.01), A61K 31/192 (2006.01), A61P 25/28 (2006.01)
Applicants: CELLZOME AG [DE/DE]; Meyerhofstrasse 1, 69117 Heidelberg (DE) (For All Designated States Except US).
RAMSDEN, Nigel [GB/GB]; (GB) (For US Only).
WILSON, Francis [GB/GB]; (GB) (For US Only).
REID, Alison [GB/GB]; (GB) (For US Only).
READER, Valerie [FR/GB]; (GB) (For US Only).
MILLER, Warren [GB/GB]; (GB) (For US Only).
HARRISON, Richard, John [GB/GB]; (GB) (For US Only).
SUNOSE, Mihiro [JP/GB]; (GB) (For US Only).
HERNANDEZ-PERNI, Remedios [ES/GB]; (GB) (For US Only).
MAJOR, Jeremy [GB/GB]; (GB) (For US Only).
BOUSSARD, Cyrille [FR/GB]; (GB) (For US Only).
SMELT, Kathryn [GB/GB]; (GB) (For US Only).
TAYLOR, Jess [GB/GB]; (GB) (For US Only).
LEFORMAL, Adeline [GB/GB]; (GB) (For US Only).
CANSFIELD, Andrew [GB/GB]; (GB) (For US Only).
BURCKHARDT, Svenja [DE/GB]; (GB) (For US Only)
Inventors: RAMSDEN, Nigel; (GB).
WILSON, Francis; (GB).
REID, Alison; (GB).
READER, Valerie; (GB).
MILLER, Warren; (GB).
HARRISON, Richard, John; (GB).
SUNOSE, Mihiro; (GB).
HERNANDEZ-PERNI, Remedios; (GB).
MAJOR, Jeremy; (GB).
BOUSSARD, Cyrille; (GB).
SMELT, Kathryn; (GB).
TAYLOR, Jess; (GB).
LEFORMAL, Adeline; (GB).
CANSFIELD, Andrew; (GB).
BURCKHARDT, Svenja; (GB)
Agent: HUHN, Michael; Isenbruck, Bösl, Hörschler, Wichmann, Huhn, Theodor-Heuss-Anlage 12, 68165 Mannheim (DE)
Priority Data:
04011851.5 19.05.2004 EP
04020132.9 25.08.2004 EP
60/642,107 10.01.2005 US
Title (EN) (BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY
(FR) ACIDES (BIPHENYL-3-YL)-CARBOXYLIQUES ET DERIVES DE CEUX-CI AINSI QUE LEUR UTILISATION EN THERAPIE
Abstract: front page image
(EN)The present invention relates to compounds having the general formula (I) with the definitions of RI-R3 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds as a medicament, preferably for the treatment of Alzheimer's disease and their use for the modulation of g-secretase activity.
(FR)L'invention concerne des composés représentés par la formule générale (I), RI-R3 étant tels que définis dans les spécifications, et/ou un sel ou un ester de ceux-ci. En outre, l'invention concerne l'utilisation de ces composés en tant que médicament, de préférence pour le traitement de la maladie d'Alzheimer, ainsi que leur utilisation pour la modulation de l'activité de la g-secrétase.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)