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1. (WO2005110475) ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/110475    International Application No.:    PCT/US2005/016357
Publication Date: 24.11.2005 International Filing Date: 10.05.2005
A61K 39/395 (2006.01), C07K 16/28 (2006.01), C12N 15/13 (2006.01)
Applicants: ABGENOMICS CORPORATION [--/--]; 2F, N0. 32, Ln. 358, Juikuang Rd., Neihu, Taipei 114 (TW) (For All Designated States Except US).
LIN, Rong-Hwa [--/--]; (TW) (For US Only).
CHANG, Chung, Nan [US/US]; (US) (For US Only).
CHEN, Pei-Jiun [--/--]; (TW) (For US Only).
HUANG, Chiu-Chen [--/--]; (TW) (For US Only)
Inventors: LIN, Rong-Hwa; (TW).
CHANG, Chung, Nan; (US).
CHEN, Pei-Jiun; (TW).
HUANG, Chiu-Chen; (TW)
Agent: GRANAHAN, Patricia; Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02110-2206 (US)
Priority Data:
60/569,892 10.05.2004 US
Abstract: front page image
(EN)Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are nucleic acids encoding the immunoglobulin chains, vectors and host cells having the nucleic acids, and methods of inducing death of an activated T cell and of modulating a T cell-mediated immune response in a subject.
(FR)Des chaînes d’immunoglobine ou des anticorps ayant une complémentarité de chaîne légère ou lourde déterminant les régions d’anticorps qui se lient à la P-sélectine glycoprotéine ligand-1. L’invention concerne également des acides nucléiques qui codent les chaînes d’immunoglobine, des vecteurs et des cellules hôtes ayant ces acides nucléiques, ainsi que des méthodes permettant de provoquer la mort d’un lymphocyte T activé et de moduler une réponse immune induite par un lymphocyte T chez un sujet.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)