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Machine translation
1. (WO2005110453) CLEAVAGE OF VEGF AND VEGF RECEPTOR BY WILDTYPE AND MUTANT MT-SP1
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/110453    International Application No.:    PCT/US2005/012488
Publication Date: 24.11.2005 International Filing Date: 12.04.2005
IPC:
C12N 9/64 (2006.01)
Applicants: CATALYST BIOSCIENCES, INC. [US/US]; 290 Utah Avenue, South San Francisco, CA 94080 (US) (For All Designated States Except US).
RUGGLES, Sandra, Waugh [US/US]; (US) (For US Only).
NGUYEN, Jack [US/US]; (US) (For US Only)
Inventors: RUGGLES, Sandra, Waugh; (US).
NGUYEN, Jack; (US)
Agent: SEIDMAN, Stephanie, L.; Fish & Richardson P.C., 12390 El Camino Real, San Diego, CA 92130 (US)
Priority Data:
60/561,720 12.04.2004 US
Title (EN) CLEAVAGE OF VEGF AND VEGF RECEPTOR BY WILDTYPE AND MUTANT MT-SP1
(FR) CLIVAGE DU VEGF ET DU RÉCEPTEUR DU VEGF PAR MT-SP1 DE TYPE SAUVAGE ET MUTANT
Abstract: front page image
(EN)MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis.
(FR)On peut utiliser des protéases de mutéines de MT-SP1 ayant une spécificité altérée pour les molécules cibles qu'elles clivent pour traiter des maladies chez l'homme, telles que le cancer. On peut utiliser le clivage du VEGF ou du VEGFR à certaines séquences de substrat avec des protéases de MT-SP1 de type sauvage et de mutéine pour traiter des pathologies associées à l'angiogenèse.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)