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1. WO2005108412 - ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS

Publication Number WO/2005/108412
Publication Date 17.11.2005
International Application No. PCT/IB2005/001186
International Filing Date 02.05.2005
Chapter 2 Demand Filed 02.03.2006
IPC
A61K 31/7048 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7048having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
C07H 17/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
17Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
04Heterocyclic radicals containing only oxygen as ring hetero atoms
08Hetero rings containing eight or more ring members, e.g. erythromycins
CPC
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
C07H 17/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
17Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
04Heterocyclic radicals containing only oxygen as ring hetero atoms
08Hetero rings containing eight or more ring members, e.g. erythromycins
Applicants
  • GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. [HR]/[HR] (AllExceptUS)
  • ALIHODZIC, Sulejman [HR]/[HR] (UsOnly)
  • MUTAK, Stjepan [HR]/[HR] (UsOnly)
  • PAVLOVIC, Drazen [HR]/[HR] (UsOnly)
  • PALEJ, Ivana [HR]/[HR] (UsOnly)
  • STIMAC, Vlado [HR]/[HR] (UsOnly)
  • KAPIC, Samra [HR]/[HR] (UsOnly)
  • VINTER, Adrijana [HR]/[HR] (UsOnly)
  • MATANOVIC SKUGOR, Maja [HR]/[HR] (UsOnly)
Inventors
  • ALIHODZIC, Sulejman
  • MUTAK, Stjepan
  • PAVLOVIC, Drazen
  • PALEJ, Ivana
  • STIMAC, Vlado
  • KAPIC, Samra
  • VINTER, Adrijana
  • MATANOVIC SKUGOR, Maja
Priority Data
60/569,40206.05.2004US
60/581,11818.06.2004US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS
(FR) MACROLIDES A LIAISON ESTER UTILES POUR LE TRAITEMENT D'INFECTION MICROBIENNES
Abstract
(EN) The present invention relates to 14- or 15-membered macrolides substituted at the 4” position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infoections in a human or animal body.
(FR) La présente invention a trait à des macrolides de 14 ou 15 chaînons substitués en position 4'' de formule (I) et des dérivés pharmaceutiquement acceptables de ceux-ci, à leurs procédés de préparation et à leur utilisation dans la thérapie ou la prophylaxie d'infections microbiennes systémiques ou topiques dans un organisme humain ou animal.
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