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1. (WO2005107708) BIODEGRADABLE INTRAVITREAL TYROSINE KINASE INHIBITORS IMPLANTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/107708    International Application No.:    PCT/US2005/015114
Publication Date: 17.11.2005 International Filing Date: 29.04.2005
Chapter 2 Demand Filed:    29.11.2005    
IPC:
A61K 9/00 (2006.01), A61K 31/00 (2006.01)
Applicants: ALLERGAN, INC. [US/US]; 2525 Dupont Drive, Irvine, CA 92612 (US) (For All Designated States Except US).
EDELMAN, Jeffrey, L. [US/US]; (US) (For US Only).
HUGHES, Patrick, M. [US/US]; (US) (For US Only).
MALONE, Thomas, C. [US/US]; (US) (For US Only).
DE VRIES, Gerald [US/US]; (US) (For US Only).
CHANG-LIN, Joan-En [US/US]; (US) (For US Only).
SHIAH, Jane, Guo [--/US]; (US) (For US Only).
NIVAGGIOLI, Thierry [US/US]; (US) (For US Only).
SPADA, Lon, T. [US/US]; (US) (For US Only).
BLANDA, Wendy, M. [US/US]; (US) (For US Only)
Inventors: EDELMAN, Jeffrey, L.; (US).
HUGHES, Patrick, M.; (US).
MALONE, Thomas, C.; (US).
DE VRIES, Gerald; (US).
CHANG-LIN, Joan-En; (US).
SHIAH, Jane, Guo; (US).
NIVAGGIOLI, Thierry; (US).
SPADA, Lon, T.; (US).
BLANDA, Wendy, M.; (US)
Agent: DONOVAN, Stephen; c/o Allergan, Inc., 2525 Dupont Drive, Irvine, CA 92612 (US)
Priority Data:
10/837,361 30.04.2004 US
11/119,001 29.04.2005 US (Considered void 23.06.2006)
  29.04.2005 US (Priority Withdrawn 18.10.2005)
  29.04.2005 US (Priority Withdrawn 18.10.2005)
Title (EN) BIODEGRADABLE INTRAVITREAL TYROSINE KINASE INHIBITORS IMPLANTS
(FR) IMPLANTS D'INHIBITEURS DE TYROSINE KINASE INTRAVITREENS, BIODEGRADABLES
Abstract: front page image
(EN)Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants can be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as posterior ocular conditions.
(FR)L'invention concerne des implants intra-oculaires biocompatibles comprenant un inhibiteur de tyrosine kinase ainsi qu'un polymère biodégradable efficace pour faciliter la libération de l'inhibiteur de tyrosine kinase dans le vitré d'un oeil sur une durée prolongée. Les agents thérapeutiques des implants peuvent être associés à une matrice polymère biodégradable, telle qu'une matrice sensiblement exempte d'alcool polyvinylique. Les implants peuvent être placés dans un oeil afin de traiter ou de réduire l'apparition d'une ou de plusieurs affections oculaires, telles que les affections d'une région oculaire postérieure.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)