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1. (WO2005107447) METHODS FOR THE PRODUCTION OF IMPROVED LIVE STOCKS AND DISEASE MODELS FOR THERAPEUTIC RESEARCH
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/107447    International Application No.:    PCT/EP2005/005103
Publication Date: 17.11.2005 International Filing Date: 11.05.2005
IPC:
A01K 67/00 (2006.01), A01K 67/027 (2006.01)
Applicants: INGENIUM PHARMACEUTICALS AG [DE/DE]; Fraunhofer Strasse 13, 82152 Martinsried (DE) (For All Designated States Except US).
NEHLS, Michael, Christian [DE/DE]; (DE) (For US Only).
WATTLER, Sigrid [DE/DE]; (DE) (For US Only).
HUFFSTADT, Ulrike [DE/DE]; (DE) (For US Only).
SEDLMEIER, Reinhard [DE/DE]; (DE) (For US Only)
Inventors: NEHLS, Michael, Christian; (DE).
WATTLER, Sigrid; (DE).
HUFFSTADT, Ulrike; (DE).
SEDLMEIER, Reinhard; (DE)
Agent: DÖRRIES, FRANK-MOLNIA & POHLMAN; Triftstrasse 13, 80538 Munich (DE)
Priority Data:
60/569,963 11.05.2004 US
60/583,676 28.06.2004 US
Title (EN) METHODS FOR THE PRODUCTION OF IMPROVED LIVE STOCKS AND DISEASE MODELS FOR THERAPEUTIC RESEARCH
(FR) PROCEDES DE PRODUCTION DE BETAIL AMELIORE ET DE MODELES PATHOLOGIQUES POUR LA RECHERCHE THERAPEUTIQUE
Abstract: front page image
(EN)The invention inter alia relates to a method of providing an embryo or a germ cell capable of producing a mutated non-human animal comprising treating sperm cells with a mutagen in vitro and contacting an oocyte with the sperm cells thus obtained. The invention also relates to an archive comprising embryos or germ cells obtained by the method of the invention, and the use of the embryo(s) or the germ cell(s) obtained or obtainable by the method of the invention for producing a non-human animal.
(FR)L'invention concerne, entre autres, un procédé permettant d'obtenir un embryon ou une cellule germinale capable de produire un animal mutant non humain, et qui comporte les étapes consistant à: traiter des cellules de sperme à l'aide d'un mutagène in vitro, et mettre un ovocyte en contact avec les cellules de sperme ainsi obtenues. L'invention concerne aussi un système de conservation comprenant les embryons ou cellules germinales obtenus grâce au procédé de l'invention, et l'utilisation du/des embryon(s) ou de la/des cellule(s) germinale(s) obtenus ou pouvant être obtenus par le procédé de l'invention pour produire un animal non humain.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)