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1. (WO2005106012) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH DIPEPTIDYL-PEPTIDASE 1 (DPP1)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/106012    International Application No.:    PCT/EP2005/004007
Publication Date: 10.11.2005 International Filing Date: 15.04.2005
IPC:
G01N 33/573 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
GEERTS, Andreas [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
GEERTS, Andreas; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
04010057.0 28.04.2004 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH DIPEPTIDYL-PEPTIDASE 1 (DPP1)
(FR) DIAGNOSTICS ET THERAPEUTIQUES DE MALADIES ASSOCIEES A LA DIPEPTIDYL-PEPTIDASE 1 (DPP1)
Abstract: front page image
(EN)The invention provides a human DPP1 which is associated with the infections, cardiovascular diseases, respiratory diseases, cancer, endocrinological diseases, metabolic diseases, gastroenterological diseases, inflammation, hematological diseases, muscle skeleton diseases, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of infections, cardiovascular diseases, respiratory diseases, cancer, endocrinological diseases, metabolic diseases, gastroenterological diseases, inflammation, hematological diseases, muscle skeleton diseases, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of DPP1 as well as pharmaceutical compositions comprising such compounds.
(FR)L'invention concerne une DPP1 humaine laquelle est associée aux infections, aux maladies cardio-vasculaires, aux maladies respiratoires, au cancer, aux maladies endocrinologiques, aux maladies métaboliques, aux maladies gastro-entérologiques, aux inflammations, aux maladies hématologiques, aux maladies des muscles du squelette, aux maladies neurologiques et aux maladies urologiques. L'invention concerne également des dosages d'identification de composés utiles dans le traitement ou la prévention d'infections, de maladies cardio-vasculaires, de maladies respiratoires, du cancer, de maladies endocrinologiques, de maladies métaboliques, de maladies gastro-entérologiques, d'inflammations, de maladies hématologiques, de maladies des muscles du squelette, de maladies neurologiques et de maladies urologiques. L'invention concerne également des composés se fixant à et/ou activant ou inhibant l'activité de DPP1, ainsi que des compositions pharmaceutiques renfermant ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)