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1. (WO2005103722) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH CXC CHEMOKINE RECEPTOR 3 (CXCR3)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/103722    International Application No.:    PCT/EP2005/004016
Publication Date: 03.11.2005 International Filing Date: 15.04.2005
IPC:
G01N 33/566 (2006.01), G01N 33/74 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
GEERTS, Andreas [DE/DE]; (DE) (For US Only).
SUMMER, Holger [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
GEERTS, Andreas; (DE).
SUMMER, Holger; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
04009261.1 20.04.2004 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH CXC CHEMOKINE RECEPTOR 3 (CXCR3)
(FR) METHODES DIAGNOSTIQUES ET THERAPEUTIQUES POUR LUTTER CONTRE LES MALADIES ASSOCIEES AU RECEPTEUR 3 DE LA CHIMIOKINE CXC (CXCR3)
Abstract: front page image
(EN)The invention provides a human CXCR3 which is associated with the gastrointestinal and liver diseases, inflammatory diseases, hematological disorders, cancer disorders, metabolic diseases and neurological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of gastrointestinal and liver diseases, inflammatory diseases, hematological disorders, cancer disorders, metabolic diseases and neurological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of CXCR3 as well as pharmaceutical compositions comprising such compounds. BHC 04 1 118-Foreign Countries
(FR)L'invention concerne un CXCR3 humain associé aux maladies gastro-intestinales et hépatiques, aux maladies inflammatoires, aux maladies hématologiques, aux maladies cancéreuses, aux maladies métaboliques ainsi qu'aux maladies neurologiques. Par ailleurs, l'invention concerne des méthodes d'analyse qui permettent d'identifier des composés utilisés dans le traitement ou la prévention des maladies cardiovasculaires, gastro-intestinales et hépatiques, des maladies inflammatoires, des maladies hématologiques, des maladies cancéreuses, des maladies métaboliques ainsi que des maladies neurologiques. De plus, l'invention concerne des composés qui se lient à et/ou qui activent ou inhibent l'activité du CXCR3 ainsi que des compositions pharmaceutiques qui renferment ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)