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1. (WO2005103710) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH CORTICOTROPIN RELEASING HORMONE RECEPTOR 1 (CRHR1)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/103710    International Application No.:    PCT/EP2005/003825
Publication Date: 03.11.2005 International Filing Date: 12.04.2005
IPC:
A61K 31/70 (2006.01), A61K 38/00 (2006.01), A61K 39/395 (2006.01), A61K 47/46 (2006.01), A61P 25/00 (2006.01), C07K 14/71 (2006.01), C12Q 1/68 (2006.01), G01N 33/68 (2006.01), G01N 33/74 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
GEERTS, Andreas [DE/DE]; (DE) (For US Only).
SUMMER, Holger [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
GEERTS, Andreas; (DE).
SUMMER, Holger; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
04009783.4 24.04.2004 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH CORTICOTROPIN RELEASING HORMONE RECEPTOR 1 (CRHR1)
(FR) METHODES DIAGNOSTIQUES ET THERAPEUTIQUES POUR LUTTER CONTRE DES MALADIES ASSOCIEES AU RECEPTEUR 1 DE L'HORMONE DE LIBERATION DE LA CORTICOTROPHINE (CRHR1)
Abstract: front page image
(EN)The invention provides a human CRHR1 which is associated with the hematological disorders, neurological disorders, developmental disorders, urological disorders and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological disorders, neurological disorders, developmental disorders, urological disorders and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of CRHR1 as well as pharmaceutical compositions comprising such compounds.
(FR)L'invention concerne un récepteur CRHR1 humain associé aux troubles hématologiques, aux troubles neurologiques, aux troubles du développement, aux troubles urologiques ainsi qu'aux troubles de la reproduction. Par ailleurs, l'invention concerne des méthodes d'analyse qui permettent d'identifier des composés utilisés dans le traitement ou la prévention des troubles hématologiques, des troubles neurologiques, des troubles du développement, des troubles urologiques ainsi que des troubles de la reproduction. De plus, l'invention concerne des composés qui se lient à et/ou qui activent ou inhibent l'activité du récepteur CRHR1 ainsi que des compositions pharmaceutiques qui renferment ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)