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Machine translation
1. (WO2005103705) CHEMOSELECTIVE FLUOROGENIC MOLECULAR LINKERS AND METHODS OF THEIR PREPARATION AND USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/103705    International Application No.:    PCT/US2005/012966
Publication Date: 03.11.2005 International Filing Date: 15.04.2005
IPC:
C07D 249/04 (2006.01), A01N 43/16 (2006.01), G01N 33/533 (2006.01), C07K 1/10 (2006.01)
Applicants: UNIVERSITY OF SOUTH CAROLINA [US/US]; Osborne Administration Building, Columbia, SC 29208 (US) (For All Designated States Except US).
WANG, Qian [CN/US]; (US) (For US Only).
SIVAKUMAR, Krishnamoorthy [IN/IN]; (IN) (For US Only)
Inventors: WANG, Qian; (US).
SIVAKUMAR, Krishnamoorthy; (IN)
Agent: NELSON MULLINS RILEY & SCARBOROUGH LLP; 1320 Main Street, 17th Floor, Columbia, SC 29201 (US)
Priority Data:
60/563,060 16.04.2004 US
60/568,804 06.05.2004 US
Title (EN) CHEMOSELECTIVE FLUOROGENIC MOLECULAR LINKERS AND METHODS OF THEIR PREPARATION AND USE
(FR) LIEURS MOLECULAIRES FLUOROGENES CHIMIOSELECTIFS ET LEURS PROCEDES DE PREPARATION ET D'UTILISATION
Abstract: front page image
(EN)The present invention describes a bioconjugation strategy and compounds that are useful therein in which a fluorescent signal is produced when two molecular or supramolecular entities are linked by chemoselective combination of one linker having an azido or halide substituent group with another linker having a cyano or an alkyne substituent group. A kit is also provided.
(FR)Une stratégie de bioconjugaison et des composés utiles dans cette stratégie au cours de laquelle un signal fluorescent est produit lorsque deux entités moléculaires ou supramoléculaires sont liées par combinaison chimiosélective d'un lieur ayant un groupe à substitution azido ou halogénure avec un autre lieur ayant un groupe à substitution cyano ou alkyne. On prévoit également un kit.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)