WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2005102269) AN AMINE DRUG-CONTAINING SLOW-RELEASE GRANULE PREPARATION BASED ON PARTICLES WITH A COATING LAYER AND THE CORRESPONDING METHOD OF PRODUCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2005/102269    International Application No.:    PCT/EP2005/003998
Publication Date: 03.11.2005 International Filing Date: 15.04.2005
IPC:
A61K 9/50 (2006.01), A61K 31/135 (2006.01), A61K 9/16 (2006.01)
Applicants: BASF AKTIENGESELLSCHAFT [DE/DE]; 67056 Ludwigshafen (DE) (For All Designated States Except US).
TANABE, Mitsunori [JP/JP]; (JP) (For US Only).
TANAKA, Tadaaki [JP/JP]; (JP) (For US Only).
YOKOTA, Kunihiko [JP/JP]; (JP) (For US Only).
KAKIGUCHI, Yoshitomi [JP/JP]; (JP) (For US Only).
KAJIURA, Tomoyoshi [JP/JP]; (JP) (For US Only)
Inventors: TANABE, Mitsunori; (JP).
TANAKA, Tadaaki; (JP).
YOKOTA, Kunihiko; (JP).
KAKIGUCHI, Yoshitomi; (JP).
KAJIURA, Tomoyoshi; (JP)
Common
Representative:
BASF AKTIENGESELLSCHAFT; 67056 Ludwigshafen (DE)
Priority Data:
04/125550 21.04.2004 JP
Title (EN) AN AMINE DRUG-CONTAINING SLOW-RELEASE GRANULE PREPARATION BASED ON PARTICLES WITH A COATING LAYER AND THE CORRESPONDING METHOD OF PRODUCTION
(FR) PREPARATIONS A LIBERATION LENTE ET LEUR PROCEDE DE PRODUCTION
Abstract: front page image
(EN)[Problem] To provide pharmaceutical preparations where the dissolution of an amine drug can be effectively controlled. [Resolution Means] Slow-release granules formed by providing a coating layer containing polyvinyl acetate and surfactant on drug-containing particles comprising an amine drug and a water-soluble binder coated onto the surface of a core material; together with a method for the production of slow-release granules which includes (i) a stage in which a liquid comprising an amine drug and a water-soluble binder dissolved or dispersed in an aqueous solvent is sprayed onto the surface of a core material and dried to form a drug layer, and (ii) a stage in which an aqueous coating liquid containing polyvinyl acetate and surfactant is sprayed onto the drug-containing particles obtained in stage (i) and dried to form a coating layer.
(FR)Cette invention vise à résoudre le problème des préparations pharmaceutiques pour lesquelles il s'agit de contrôler efficacement la dissolution d'un médicament amine. A cet effet, on forme des granules à libération lente en appliquant une couche d'enrobage contenant de l'acétate de polyvinyle et un tensioactif sur des particules contenant le médicament comprenant un médicament amine et un liant hydrosoluble venant recouvrir la surface d'un matériau noyau; et on utilise une procédé de production de granules à libération lente, qui comprend: (i) une étape dans laquelle un liquide comprenant un médicament amine et un liant hydrosoluble dissout ou dispersé dans un solvant aqueux est pulvérisé sur la surface d'un matériau noyau et séché pour former une couche de médicament; et (ii) une étape dans laquelle un liquide d'enrobage aqueux contenant de l'acétate de polyvinyle et un tensioactif est pulvérisé sur les particules contenant le médicament obtenues dans l'étape (i) et séchées pour former une couche d'enrobage.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)