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1. WO2005100593 - A METHOD FOR MONITORING THE PROGRESS OF CANCER

Publication Number WO/2005/100593
Publication Date 27.10.2005
International Application No. PCT/AU2005/000542
International Filing Date 15.04.2005
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 33/574 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
G01N 33/74 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
74involving hormones
CPC
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
C12Q 2600/112
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
112Disease subtyping, staging or classification
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
G01N 33/57434
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
57407Specifically defined cancers
57434of prostate
Applicants
  • MONASH UNIVERSITY [AU]/[AU] (AllExceptUS)
  • RISBRIDGER, Gail Petuna [AU]/[AU] (UsOnly)
  • MELLOR, Sally Louise [AU]/[AU] (UsOnly)
  • BALL, Emma Margaret Anne [AU]/[AU] (UsOnly)
  • WANG, Hong [AU]/[AU] (UsOnly)
  • PEDERSEN, John Stuart [AU]/[AU] (UsOnly)
  • MCLEAN, Catriona [AU]/[AU] (UsOnly)
Inventors
  • RISBRIDGER, Gail Petuna
  • MELLOR, Sally Louise
  • BALL, Emma Margaret Anne
  • WANG, Hong
  • PEDERSEN, John Stuart
  • MCLEAN, Catriona
Agents
  • OBRANOVICH, Tania, D
Priority Data
60/562,71516.04.2004US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A METHOD FOR MONITORING THE PROGRESS OF CANCER
(FR) PROCEDE DESTINE A REGULER LA PROGRESSION D'UN CANCER
Abstract
(EN)
The present invention relates generally to a method of diagnosing, predicting or monitoring the development or progress of a cancer and, in particular, to a method of diagnosing, predicting or monitoring the development of or progress of prostate cancer in a mammal. The present invention more specifically provides a method for delineating early stage and advanced stage cancers, or predispositions thereto, by screening for changes in the level of two or more of inhibin-&agr;, activin-&bgr;A, activin-&bgr;B, activin-&bgr;C, activin-&bgr;D, activin-&bgr;E or follistatin expression in a mammal. The present invention further provides a method for diagnosing or monitoring conditions associated with or characterized by the onset of a cancer.
(FR)
L'invention concerne, de façon générale, un procédé de diagnostic, de prédiction ou de régulation du développement ou de la progression d'un cancer, et plus particulièrement, un procédé de diagnostic, de prédiction ou de régulation du développement ou du progrès d'un cancer de la prostate chez un mammifère. Cette invention concerne, plus spécifiquement, un procédé destiné à repérer les cancers en stade précoce et en stade avancé, ou des prédispositions aux cancers, par criblage de changements dans le niveau de deux ou plusieurs expressions d'inhibine-$g(a), d'activine-$g(b)A, d'activine-$g(b)B, d'activine-$g(b)C, d'activine-$g(b)D, d'activine-$g(b)E ou de follistatine chez un mammifère. Cette invention concerne également un procédé destiné à diagnostiquer ou à réguler des états associés ou caractérisés par l'apparition d'un cancer.
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