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1. WO2005097164 - USE OF CYCLOSPORINS FOR TREATMENT OF CEREBRAL ISCHEMIA AND BRAIN AND SPINAL CORD INJURY

Publication Number WO/2005/097164
Publication Date 20.10.2005
International Application No. PCT/EP2005/003664
International Filing Date 07.04.2005
IPC
A61K 38/13 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides
13Cyclosporins
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
CPC
A61K 38/13
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides ; , e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
13Cyclosporins
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 9/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applicants
  • NOVARTIS AG [CH]/[CH] (AE, AG, AL, AM, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW)
  • NOVARTIS PHARMA GMBH [AT]/[AT] (AT)
  • WALDMEIER, Peter [CH]/[CH] (UsOnly)
Inventors
  • WALDMEIER, Peter
Agents
  • VON SPRECHER, Georg
Priority Data
60/560,46508.04.2004US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF CYCLOSPORINS FOR TREATMENT OF CEREBRAL ISCHEMIA AND BRAIN AND SPINAL CORD INJURY
(FR) NIM811 UTILISE DANSLA PREVENTION OU LE TRAITEMENT DE L'ISCHEMIE CEREBRALE ET DE LESIONS CEREBRALES ET DE LA MOELLE EPINIERE
Abstract
(EN)
Non-immunosuppresssive, cyclophilin-binding cyclosporins, in particular, [Melle]4-Ciclosporin, are useful as neuroprotective agents, e.g., in the prevention or treatment of cerebral ischemia or traumatic brain or spinal cord injury.
(FR)
L'invention concerne des cyclosporines à liaison cyclophiline, non-immunosuppressive, notamment de la cyclosporine [Melle]4, utilisées en tant qu'agents neuroprotecteurs, notamment, dans la prévention ou le traitement de l'ischémie cérébrale ou de lésions cérébrales traumatiques ou de la moelle épinière.
Latest bibliographic data on file with the International Bureau