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1. WO2005094384 - METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES

Publication Number WO/2005/094384
Publication Date 13.10.2005
International Application No. PCT/US2005/011010
International Filing Date 30.03.2005
IPC
A61K 31/74 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
A61K 47/30 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
A61K 9/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
A61K 9/32 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
28Dragees; Coated pills or tablets
30Organic coatings
32containing solid synthetic polymers
A61K 9/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
28Dragees; Coated pills or tablets
A61K 9/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
CPC
A61K 31/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
A61K 31/78
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
765Polymers containing oxygen
78of acrylic acid or derivatives thereof
A61K 31/785
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
785Polymers containing nitrogen
A61K 31/795
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
795Polymers containing sulfur
A61K 31/80
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
74Synthetic polymeric materials
80Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants
  • ILYPSA, INC. [US]/[US] (AllExceptUS)
  • ALPERN, Robert [US]/[US] (UsOnly)
  • BUYSSE, Jerry, M. [US]/[US] (UsOnly)
  • CHANG, Han, Ting [--]/[US] (UsOnly)
  • CHARMOT, Dominique [FR]/[US] (UsOnly)
  • COPE, Michael, James [IE]/[US] (UsOnly)
  • FORDTRAN, John [US]/[US] (UsOnly)
  • KLAERNER, Gerrit [DE]/[US] (UsOnly)
Inventors
  • ALPERN, Robert
  • BUYSSE, Jerry, M.
  • CHANG, Han, Ting
  • CHARMOT, Dominique
  • COPE, Michael, James
  • FORDTRAN, John
  • KLAERNER, Gerrit
Agents
  • ROCHE, Anie, K.
Priority Data
10/813,87230.03.2004US
10/814,52730.03.2004US
10/814,74930.03.2004US
10/965,27413.10.2004US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES
(FR) PROCEDES ET COMPOSITIONS POUR LE TRAITEMENT DE DESEQUILIBRES IONIQUES
Abstract
(EN)
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium­binding polymers and pharmaceutical compositions thereof Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.
(FR)
L'invention concerne des procédés et des compositions pour le traitement de déséquilibres ioniques. Plus spécifiquement, l'invention concerne des compositions comprenant des polymères de liaison au sodium et des compositions pharmaceutiques de celles-ci. L'invention concerne également des procédés d'utilisation de ces compositions polymériques et pharmaceutiques dans des buts thérapeutiques et/ou prophylactiques. Des exemples de ces procédés comprennent le traitement de l'hypertension, de l'insuffisance cardiaque chronique, d'une maladie rénale en phase finale, de la cirrhose du foie, d'une insuffisance rénale chronique, d'une surcharge fluidique, ou d'une surcharge de sodium.
Latest bibliographic data on file with the International Bureau