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1. (WO2005087738) BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS

Pub. No.:    WO/2005/087738    International Application No.:    PCT/US2005/007988
Publication Date: Fri Sep 23 01:59:59 CEST 2005 International Filing Date: Fri Mar 11 00:59:59 CET 2005
IPC: C07D 211/62
Applicants: THERAVANCE, INC.
MAMMEN, Mathai
JI, Yu-Hua
MU, YongQi
HUSFELD, Craig
LI, Li
Inventors: MAMMEN, Mathai
JI, Yu-Hua
MU, YongQi
HUSFELD, Craig
LI, Li
Title: BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS
Abstract:
This invention provides compounds of formula (I): wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula (I) are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.